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80 岁以上老年人行微创经椎间孔腰椎体间融合术的安全性如何?:围手术期并发症分析。

How Safe Is Minimally Invasive Transforaminal Lumbar Interbody Fusion for Octogenarians?: A Perioperative Complication Analysis.

机构信息

Department of Neurosurgery, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Department of Neurosurgery, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

出版信息

World Neurosurg. 2020 Jul;139:e754-e760. doi: 10.1016/j.wneu.2020.04.128. Epub 2020 Apr 25.

Abstract

BACKGROUND

Technical advances in minimally invasive spine surgery have reduced blood loss, access trauma, and postoperative length of stay. However, operating on the susceptible group of octogenarians still poses a dilemma because of a plethora of age-related comorbidities. The aim of this study was to investigate the safety of minimally invasive surgery (MIS) transforaminal lumbar interbody fusion (TLIF) in octogenarians.

METHODS

We conducted a retrospective single-center study of all patients over 80 years of age who, between March 2009 and February 2014, had undergone MIS TLIF. The primary outcome was recorded major and minor complications within 30 days of surgery.

RESULTS

Twenty-one patients with an average age of 84.1 ± 2.7 years underwent MIS TLIF in 31 levels for degenerative lumbar disk disease with intolerable pain after failure of conservative treatment. Of the patients, 33.3% showed no perioperative complications. In the remaining 66.7%, 6 major complications and 24 minor complications occurred within 30 days of surgery. Two of these patients died within 30 days of surgery because of sepsis and pulmonary embolism (mortality rate 9.5%).

CONCLUSIONS

Our study spotlighted the susceptible group of octogenarians and evaluated the safety of MIS TLIF. The perioperative morbidity for octogenarians undergoing MIS TLIF is substantial and even higher than for patients over 65 years of age. Two thirds of patients in this subgroup suffer at least 1 complication. The 30-day mortality rate was 9.5%. Therefore, it is advisable for these patients to exploit all available conservative options prior to surgery.

摘要

背景

微创脊柱手术技术的进步减少了术中出血量、手术入路创伤和术后住院时间。然而,由于与年龄相关的多种合并症,对 80 岁以上的易感人群进行手术仍然存在困境。本研究旨在探讨微创经椎间孔腰椎体间融合术(MIS TLIF)治疗 80 岁以上高龄患者的安全性。

方法

我们对 2009 年 3 月至 2014 年 2 月期间在我院接受过 MIS TLIF 的所有 80 岁以上患者进行了回顾性单中心研究。主要结果为记录手术 30 天内的主要和次要并发症。

结果

21 例患者平均年龄为 84.1 ± 2.7 岁,因退行性腰椎间盘疾病导致无法忍受的疼痛,且经保守治疗失败后接受了 MIS TLIF,共 31 个节段。患者中 33.3%无围手术期并发症。在其余 66.7%的患者中,6 例出现主要并发症,24 例出现次要并发症,均发生在术后 30 天内。其中 2 例患者因脓毒症和肺栓塞在术后 30 天内死亡(死亡率 9.5%)。

结论

本研究聚焦于 80 岁以上的易感人群,并评估了 MIS TLIF 的安全性。接受 MIS TLIF 的 80 岁以上高龄患者的围手术期发病率较高,甚至高于 65 岁以上患者。该亚组中有三分之二的患者至少发生 1 种并发症。30 天死亡率为 9.5%。因此,建议这些患者在手术前充分利用所有可行的保守治疗方案。

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