Liggins Institute, University of Auckland, Auckland, New Zealand.
Exercise Sciences Department, University of Auckland, Auckland, New Zealand.
Phys Occup Ther Pediatr. 2021;41(1):44-55. doi: 10.1080/01942638.2020.1758983. Epub 2020 Apr 28.
To evaluate the effects of side-alternating vibration therapy on physical function and body composition in adolescents with Down syndrome.
Fourteen adolescents (8 males) with Down syndrome (mean ± SD age: 15.5 ± 2.3 years) performed vibration treatment nine minutes daily, four times per week, for 20 weeks on a Galileo vibration platform. Data were collected at baseline and after 20 weeks of intervention. Assessments included six-minute walk test, muscle function (force plate), whole-body dual-energy X-ray absorptiometry and peripheral quantitative computed tomography of the non-dominant tibia.
After 20 weeks, participants increased their distance walked in the six-minute walk test ( = 0.009), 2-leg single jump efficiency ( = 0.024) and jump velocity ( = 0.046). Participants also increased their power ( = 0.034) and reduced the time taken during the chair rise test ( < 0.001). At the total body level, increases were seen in bone mineral density ( = 0.004), bone mineral content ( = 0.043), fat free mass ( = 0.013) and lean mass ( = 0.021).
Side-alternating vibration therapy was associated with increases in physical function and muscle mass with no effects on bone health in adolescents with Down syndrome.
Australian New Zealand Clinical Trial Registry (ACTRN12615000092594) - registered on 4 February 2015.
评估交替侧振疗法对唐氏综合征青少年身体功能和身体成分的影响。
14 名唐氏综合征青少年（8 名男性）（平均年龄±标准差：15.5±2.3 岁）每天进行 9 分钟、每周 4 次、共 20 周的伽利略振动平台振动治疗。在基线和 20 周干预后收集数据。评估包括 6 分钟步行测试、肌肉功能（力量板）、全身双能 X 射线吸收法和非优势胫骨的外周定量计算机断层扫描。
20 周后，参与者在 6 分钟步行测试中增加了步行距离（ = 0.009）、2 腿单跳效率（ = 0.024）和跳跃速度（ = 0.046）。参与者还增加了力量（ = 0.034），并减少了从椅子上站起来的时间（ < 0.001）。在全身水平上，骨密度（ = 0.004）、骨矿物质含量（ = 0.043）、无脂肪质量（ = 0.013）和瘦体重（ = 0.021）均有所增加。
交替侧振疗法与唐氏综合征青少年身体功能和肌肉质量的增加有关，对骨骼健康没有影响。
澳大利亚新西兰临床试验注册中心（ACTRN12615000092594）-于 2015 年 2 月 4 日注册。
