Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia.
Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Australia.
J Obstet Gynaecol. 2021 Feb;41(2):169-175. doi: 10.1080/01443615.2020.1734781. Epub 2020 Apr 29.
Most adnexal masses are benign, incidental findings of pregnancy which resolve spontaneously. They may present clinically due to haemorrhage, rupture, torsion and mass effect. Aetiological classification includes ovarian benign, ovarian malignant, non-ovarian, gynaecological, non-ovarian non-gynaecological and an additional subset of pathologies unique to pregnancy. Ultrasound is the first-line imaging modality for the evaluation of adnexal masses. This may be supplemented with magnetic resonance imaging. Tumour markers support evaluation of malignant potential, but interpretation of results in pregnancy is challenging. Surgical intervention requires consideration of gestation, lesion characteristics and presence of complications. Laparoscopy is preferred owing to shorter operative time, quicker recovery and resultant lower thrombotic risk. Post-viability, fetal wellbeing and assessment must be considered. Management of the pregnancy may include cardiotocography, steroids, non-teratogenic antibiotics and tocolytics. In rare cases, particularly related to malignancy, termination of pregnancy may be required to enable immediate management where there are concerns for maternal wellbeing.
大多数附件肿块是妊娠的良性、偶发发现,会自行消退。它们可能因出血、破裂、扭转和肿块效应而出现临床症状。病因分类包括卵巢良性、卵巢恶性、非卵巢、妇科、非卵巢非妇科以及妊娠特有的一组特定病理学。超声是评估附件肿块的一线影像学方法。可以补充磁共振成像。肿瘤标志物有助于评估恶性潜能,但在妊娠期间解释结果具有挑战性。手术干预需要考虑妊娠、病变特征和并发症的存在。由于手术时间更短、恢复更快,血栓形成风险更低,因此首选腹腔镜检查。存活后,必须考虑胎儿的健康状况和评估。妊娠的管理可能包括胎心监护、类固醇、非致畸抗生素和保胎药。在极少数情况下,特别是与恶性肿瘤相关的情况下,可能需要终止妊娠,以便在出现母亲健康问题时能够立即进行管理。