Toner B B, Garfinkel P E, Garner D M
Clarke Institute of Psychiatry, University of Toronto.
Int J Psychiatry Med. 1988;18(4):357-64. doi: 10.2190/934q-eppl-keyg-nn0u.
This study investigated the incidence and onset of affective and anxiety disorders in women who were diagnosed with anorexia nervosa five to fourteen years earlier. Based on the clinical outcome of anorexia nervosa, patients were classified as asymptomatic, improved or symptomatic. Affective and anxiety disorders were assessed by a structured psychiatric interview (Diagnostic Interview Schedule). Results indicated that affective and anxiety disorders developed frequently, regardless of outcome of anorexia nervosa. Major depression and anxiety disorders developed before the eating disorder in one-half and three-quarters of these cases respectively. The symptomatic group had a significantly higher incidence of anxiety disorders prior to the development of their eating disorder compared with the asymptomatic group.
本研究调查了5至14年前被诊断为神经性厌食症的女性中情感障碍和焦虑症的发病率及发病情况。根据神经性厌食症的临床结果，患者被分为无症状、病情改善或有症状三类。情感障碍和焦虑症通过结构化精神科访谈（诊断访谈表）进行评估。结果表明，无论神经性厌食症的结果如何，情感障碍和焦虑症都很常见。在这些病例中，分别有一半和四分之三的患者在饮食失调之前就出现了重度抑郁症和焦虑症。与无症状组相比，有症状组在饮食失调之前焦虑症的发病率明显更高。
