Zieske L A, Myers E N, Brown B M
Otolaryngology-Head and Neck Surgery Service, Tripler Army Medical Center, Honolulu, Hawaii 96859-5000.
Head Neck Surg. 1988 Jan-Feb;10(3):195-8. doi: 10.1002/hed.2890100308.
Although pulmonary lymphangitic carcinomatosis (PLC) is not uncommon for breast, bronchial, and stomach cancers, it is rarely associated with head and neck malignancy. A case of PLC is reported with the primary lesion being an adenosquamous carcinoma of the hypopharynx. A literature review is discussed, highlighting the varied radiographic picture of PLC, the possible diagnostic modalities, the proposed pathogenesis, and the treatment options. The prognosis even if antemortum diagnosis and treatment are given remains fatal, although with temporary improved quality of life and lengthened survival. There is hope that with greater awareness of the disease process an increased incidence of diagnosis may allow progress to be made in therapeutic interventions.
尽管肺淋巴管癌病（PLC）在乳腺癌、支气管癌和胃癌中并不罕见，但它很少与头颈部恶性肿瘤相关。本文报告了一例以下咽腺鳞癌为原发灶的PLC病例。并对文献进行了综述，重点介绍了PLC多样的影像学表现、可能的诊断方法、推测的发病机制以及治疗选择。即使在生前进行诊断和治疗，预后仍然是致命的，尽管生活质量会暂时改善，生存期会延长。希望随着对该疾病过程的更多认识，诊断率的提高可能会在治疗干预方面取得进展。
