气相色谱法测定动物肝脏中五氯苯酚的验证研究。

Validation study of gas chromatographic determination of pentachlorophenol in animal liver.

作者信息

Gillard D, Epstein R L, Ashworth R B, Curry K, Nathan Q

机构信息

Huntingdon Analytical Services, Middleport, NY 14105.

出版信息

J Assoc Off Anal Chem. 1988 Sep-Oct;71(5):926-9.

PMID:3235410

Abstract

A validation study was conducted of a gas chromatographic procedure for the determination of pentachlorophenol (PCP) in chicken, pork, and beef liver. Five analysts representing 5 laboratories analyzed randomly numbered blind duplicates at 3 fortified tissue concentrations and one incurred tissue on 2 consecutive days. The PCP concentrations ranged from approximately 40 to 400 parts per billion (ppb). All data were reported to 3 significant figures in ppb. The coefficients of variation for repeatability were between 2.8 and 8.5%, except for the beef liver, at a mean value of 80 ppb PCP, where the CV was 11.3%. The CVs for reproducibility were in the range of 9.7-16.5% with little significant difference by species. The CV asymptotically approached 10% as the PCP level increased.

摘要

开展了一项验证研究，以评估一种气相色谱法用于测定鸡肉、猪肉和牛肝中五氯苯酚（PCP）的效果。来自5个实验室的5名分析人员在连续两天内，对3种加标组织浓度的随机编号盲样复制品以及1份实际污染组织进行了分析。PCP浓度范围约为十亿分之40至400（ppb）。所有数据均以ppb为单位报告至3位有效数字。除牛肝外，重复性变异系数在2.8%至8.5%之间，牛肝中PCP平均值为80 ppb时，变异系数为11.3%。再现性变异系数在9.7%至16.5%范围内，不同物种间差异不显著。随着PCP水平的升高，变异系数渐近接近10%。