氟司喹南和硝苯地平对健康志愿者糖耐量的影响。
The effects of flosequinan and nifedipine on glucose tolerance in healthy volunteers.
作者信息
Lewis H, Kendall M, Bratty J R
机构信息
Department of Pharmacology, University of Birmingham, Medical School, Edgbaston, U.K.
出版信息
J Clin Pharm Ther. 1988 Aug;13(4):269-72. doi: 10.1111/j.1365-2710.1988.tb00192.x.
The influence of flosequinan and nifedipine on glucose tolerance has been investigated in a placebo-controlled four-way crossover study in 12 healthy volunteers. There was no statistical difference between the glucose tolerance curves after placebo, a single dose of flosequinan, chronic treatment with flosequinan or nifedipine at steady state. Headache was more frequent in volunteers on flosequinan than after either nifedipine or placebo.
在一项安慰剂对照的四交叉研究中，对12名健康志愿者研究了氟司喹南和硝苯地平对葡萄糖耐量的影响。安慰剂、单剂量氟司喹南、氟司喹南稳态慢性治疗或硝苯地平治疗后的葡萄糖耐量曲线之间无统计学差异。服用氟司喹南的志愿者比服用硝苯地平或安慰剂的志愿者头痛更频繁。
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