Department of Research and Development, CIRO, Horn, the Netherlands (Mss Delbressine and Goërtz, and Drs Vaes, Sillen, Janssen, and Spruit); Department of Rehabilitation, Akita City Hospital, Kawamoto Matsuoka-cho, Akita, Japan (Dr Kawagoshi); NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, the Netherlands (Drs Meijer and Spruit); Department of Health Services Research, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands (Dr Janssen); Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands (Dr Spruit); and REVAL-Rehabilitation Research Center, BIOMED-Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium (Dr Spruit).
J Cardiopulm Rehabil Prev. 2020 May;40(3):152-163. doi: 10.1097/HCR.0000000000000513.
Chronic obstructive pulmonary disease (COPD) is a highly prevalent disease characterized by airflow limitation and is associated with decreased balance and increased fall risk. Since falls are related to increased mortality, interventions targeting balance and fall risk could reduce morbidity and mortality. The objective of this review was to systematically assess the effects of exercise-based interventions on fall risk and balance in patients with COPD.
PubMed, Web of Science, EMBASE, and CINAHL were screened for randomized controlled trails and within-group studies evaluating effects of exercise-based interventions on fall risk or balance in patients with COPD. Data were presented in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.
Fifteen studies were identified, 6 randomized controlled trails and 9 within-group studies. All interventions reported positive effects on balance outcomes. No studies reported fall risk. Taking current recommendations of balance outcome measures in patients with COPD into account, pulmonary rehabilitation combined with balance training had the highest effect size. Nine papers had concerns regarding bias, mostly due to the lack of blinding outcome assessors.
Exercise-based interventions have a positive effect on balance in patients with COPD. Pulmonary rehabilitation with balance training seems to have the most beneficial effect on balance. The effects on fall risk, as well as the long-term intervention effects remain unclear. A standardized balance assessment and research on long-term effects and fall risk are recommended.
慢性阻塞性肺疾病(COPD)是一种高发疾病,其特征是气流受限,并与平衡能力下降和跌倒风险增加有关。由于跌倒与死亡率增加有关,针对平衡和跌倒风险的干预措施可以降低发病率和死亡率。本综述的目的是系统评估基于运动的干预措施对 COPD 患者跌倒风险和平衡能力的影响。
在 PubMed、Web of Science、EMBASE 和 CINAHL 上筛选了评估基于运动的干预措施对 COPD 患者跌倒风险或平衡能力影响的随机对照试验和组内研究。数据按照系统评价和荟萃分析的首选报告项目呈现。
确定了 15 项研究,其中 6 项为随机对照试验,9 项为组内研究。所有干预措施均报告对平衡结果有积极影响。没有研究报告跌倒风险。考虑到 COPD 患者平衡结果测量的当前建议,肺康复结合平衡训练的效果大小最高。9 篇论文存在偏倚问题,主要是因为缺乏对结果评估者的盲法。
基于运动的干预措施对 COPD 患者的平衡有积极影响。肺康复结合平衡训练似乎对平衡有最有益的影响。跌倒风险的影响以及长期干预效果仍不清楚。建议进行标准化的平衡评估,并研究长期效果和跌倒风险。