季铵托烷衍生物氯化曲司氯铵的放射免疫分析
Radioimmunoassay of trospiumchloride, a quaternary tropane derivative.
作者信息
Lehtola T, Lavikainen O, Huhtikangas A
机构信息
Department of Pharmaceutical Chemistry, University of Kuopio, Finland.
出版信息
J Immunoassay. 1988;9(3-4):297-307. doi: 10.1080/01971528808053218.
PMID:3235686
Abstract
A specific radioimmunoassay (RIA) has been developed for the determination of picogram amounts of trospiumchloride, an anticholinergic agent, from unpurified serum and urine samples. Practically no interference was observed for various potential crossreacting compounds tested. The method is sensitive and excellent values for accuracy, precision and correlation were obtained.
摘要
已开发出一种特定的放射免疫分析法（RIA），用于从未纯化的血清和尿液样本中测定皮克量的抗胆碱能药物曲司氯铵。对于所测试的各种潜在交叉反应化合物，几乎未观察到干扰。该方法灵敏，在准确性、精密度和相关性方面均获得了优异的值。
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