Institute for Autism Research, Canisius College, Science Hall 1016C, 2001 Main Street, Buffalo, NY, 14208, USA.
Center for Research in Autism, Intellectual, and Other Neurodevelopmental Disabilities, Michigan State University, East Lansing, MI, USA.
J Abnorm Child Psychol. 2020 Aug;48(8):1105-1114. doi: 10.1007/s10802-020-00652-5.
A prior cluster randomized controlled trial (RCT) compared outcomes for a comprehensive school intervention (schoolMAX) to typical educational programming (services-as-usual [SAU]) for 103 children with autism spectrum disorder (ASD) without intellectual disability. The schoolMAX intervention was superior to SAU in improving social-cognitive understanding (emotion-recognition), social/social-communication skills, and ASD-related impairment (symptoms). In the current study, a range of demographic, clinical, and school variables were tested as potential moderators of treatment outcomes from the prior RCT. Moderation effects were not evident in demographics, child IQ, language, or ASD diagnostic symptoms, or school SES. Baseline externalizing symptoms moderated the outcome of social-cognitive understanding and adaptive skills moderated the outcome of ASD-related symptoms (no other comorbid symptoms or adaptive skills ratings moderated outcomes on the three measures). Overall, findings suggest that the main effects of treatment were, with two exceptions, unaffected by third variables.
先前的一项整群随机对照试验(RCT)比较了 103 名自闭症谱系障碍(ASD)儿童的综合学校干预(schoolMAX)与典型教育计划(常规服务 [SAU])的结果,这些儿童没有智力障碍。schoolMAX 干预在改善社会认知理解(情绪识别)、社会/社会沟通技能和 ASD 相关障碍(症状)方面优于 SAU。在当前的研究中,研究人员测试了一系列人口统计学、临床和学校变量,以检验这些变量是否能调节先前 RCT 的治疗结果。在人口统计学、儿童智商、语言或 ASD 诊断症状或学校社会经济地位方面,没有明显的调节作用。基线外化症状调节社会认知理解的结果,适应技能调节 ASD 相关症状的结果(其他共病症状或适应技能评定没有调节三个评定指标的结果)。总的来说,这些发现表明,治疗的主要效果,除了两个例外,不受第三变量的影响。