Department of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
Department of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
Clin Biomech (Bristol). 2020 May;75:105000. doi: 10.1016/j.clinbiomech.2020.105000. Epub 2020 Apr 21.
Although brain, one of the most complex organs in the mammalian body, has been subjected to many studies from physiological and pathological points of view, there remain significant gaps in the available knowledge regarding its biomechanics. This article reviews the research trends in brain biomechanics with a focus on injury. We used published scientific articles indexed by Web of Science database over the past 40 years and tried to address the gaps that still exist in this field. We analyzed the data using VOSviewer, which is a software tool designed for scientometric studies. The results of this study showed that the response of brain tissue to external forces has been one of the significant research topics among biomechanicians. These studies have addressed the effects of mechanical forces on the brain and mechanisms of traumatic brain injury, as well as characterized changes in tissue behavior under trauma and other neurological diseases to provide new diagnostic and monitoring methods. In this study, some challenges in the field of brain injury biomechanics have been identified and new directions toward understanding the gaps in this field are suggested.
虽然大脑是哺乳动物体内最复杂的器官之一，已经从生理和病理角度进行了许多研究，但关于其生物力学仍存在很大的知识空白。本文综述了脑生物力学的研究趋势，重点关注损伤。我们使用了过去 40 年来被 Web of Science 数据库索引的已发表的科学文章，并试图解决该领域仍存在的差距。我们使用 VOSviewer 分析了这些数据，VOSviewer 是一款专门用于科学计量学研究的软件工具。本研究结果表明，脑组织对外力的反应一直是生物力学学家的重要研究课题之一。这些研究探讨了机械力对大脑的影响和创伤性脑损伤的机制，以及在创伤和其他神经疾病下组织行为的变化，为提供新的诊断和监测方法提供了依据。在本研究中，确定了脑损伤生物力学领域的一些挑战，并提出了理解该领域差距的新方向。
