Imen Ben Ismail, Zenaidi Hakim, Abdelwahed Yahmadi, Sabeur Rebii, Ayoub Zoghlami
Department of General Surgery, Trauma and Burns Center, Ben Arous, Tunisia.
Int J Surg Case Rep. 2020;70:24-27. doi: 10.1016/j.ijscr.2020.03.048. Epub 2020 Apr 22.
Castleman's disease (CD) is a rare disorder characterized by benign angio follicular lymphoid hyperplasia, with gentle behavior. Its etiology and prevalence are unclear. It is usually found in the mediastinal area and it is rare to see this tumor in the retroperitoneum.
A 53 year old male with a retroperitoneal hypervascular calcified mass densely adherent to the psoas muscle that was accidentally encountered on a CT scan. Provisional diagnosis of retroperitoneal liposarcoma was made and the patient underwent an exploratory laparotomy. The histologic examination of the surgically resected specimen disclosed « a hyaline type of Castleman's disease ».
Castleman's disease, is a rare heterogenous group of lymphoproliferative disorders that arises mostly in the mediastinum. The retroperitoneal localization is very rare. Clinically, CD can be subdivided into a localized form (unicentric disease) and a generalized form (multicentric disease) according to the number of lymph nodes involved. A careful histological and immunohistochemical examination of the tumor tissue after surgery is the only way for tumor diagnosis.
Castelman's disease is a rare entity that has often benign and non invasive behavior, but remains a diagnostic challenge. There is no reliable diagnostic method and its definitive diagnosis is based on histopathology report. For treating the unicentric variant, radical surgical resection is considered to be the gold standard.
Castleman病（CD）是一种罕见的疾病，其特征为良性血管滤泡性淋巴组织增生，病程发展缓慢。其病因和发病率尚不清楚。该病通常见于纵隔区域，而在腹膜后发现此肿瘤则较为罕见。
一名53岁男性，在CT扫描时意外发现腹膜后有一与腰大肌紧密粘连的富血管钙化肿块。初步诊断为腹膜后脂肪肉瘤，患者接受了剖腹探查术。手术切除标本的组织学检查显示为“透明型Castleman病”。
Castleman病是一组罕见的异质性淋巴增生性疾病，主要发生于纵隔。腹膜后定位非常罕见。临床上，根据受累淋巴结的数量，CD可分为局限性（单中心疾病）和全身性（多中心疾病）两种类型。术后对肿瘤组织进行仔细的组织学和免疫组化检查是诊断肿瘤的唯一方法。
Castleman病是一种罕见的疾病，通常具有良性和非侵袭性的行为，但仍然是一个诊断难题。目前尚无可靠的诊断方法，其确诊依赖于组织病理学报告。对于单中心型的治疗，根治性手术切除被认为是金标准。
