Steinhardt G F, Vogler G, Salinas-Madrigal L, LaRegina M
Department of Surgery, St Louis University School of Medicine.
J Pediatr Surg. 1988 Dec;23(12):1127-30. doi: 10.1016/s0022-3468(88)80327-0.
Using the North American opossum, Didelphis virginiana, we have developed a new model for studying the effects of early fetal urinary obstruction on subsequent renal development. We have successfully induced renal dysplasia in the marsupial that has a typically mammalian kidney.
利用北美负鼠(弗吉尼亚负鼠),我们开发了一种新模型,用于研究早期胎儿尿路梗阻对后续肾脏发育的影响。我们已成功在具有典型哺乳动物肾脏的有袋动物中诱发肾发育异常。