Division of Physical Medicine and Rehabilitation, University of British Columbia, Victoria, British Columbia, Canada.
Department of Family Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Can J Neurol Sci. 2020 Sep;47(5):697-699. doi: 10.1017/cjn.2020.88. Epub 2020 May 4.
Ischemic monomelic neuropathy (IMN) is a little-known, painful axonal neuropathy, secondary to vascular occlusion or steal phenomenon. It typically occurs after vascular bypass, hemodialysis fistulization, or diabetic microvascular disease in the absence of significant clinical features of ischemia. There is limited literature to assist in the characterization and diagnosis of this condition. We describe three patients with IMN with no surgical or peripheral vascular disease history who exhibited spontaneous, persistent foot pain, edema numbness, and weakness with denervation on needle electromyogram in a distal lower leg peripheral nerve distribution. Occlusive disease was found in all patients on angiogram, requiring vascular bypass surgery.
缺血性单发性神经病（IMN）是一种鲜为人知的、疼痛性轴索性神经病，继发于血管闭塞或盗血现象。它通常发生在血管旁路、血液透析瘘管形成或糖尿病微血管疾病之后，而没有明显的缺血临床特征。目前文献有限，难以对这种情况进行特征描述和诊断。我们描述了 3 例 IMN 患者，他们均无手术或外周血管疾病史，表现为自发性、持续性足部疼痛、肿胀、麻木和无力，下肢远端周围神经分布处的肌电图显示失神经支配。所有患者的血管造影均发现阻塞性疾病，需要进行血管旁路手术。
