Hreńczuk Marta, Biedrzycka Anna, Łągiewska Beata, Kosieradzki Maciej, Małkowski Piotr
Department of Surgical and Transplantation Nursing, and Extracorporeal Treatment, Faculty of Health Sciences, Medical University of Warsaw, Poland.
Faculty of Health Sciences, Medical University of Warsaw, Poland.
Transplant Proc. 2020 Oct;52(8):2497-2502. doi: 10.1016/j.transproceed.2020.02.093. Epub 2020 May 1.
The aim of the study was a single-center assessment of occurrence of surgical site infections (SSI) in patients after liver transplantation and an attempt to determine factors that may contribute to this complication.
Analysis of medical records of 60 adult patients, who underwent first transplantation in 2016 and 2017 was conducted. Selected pre-, intra-, and postoperative factors were assessed. Statistical analysis was performed with StatSoft Statistica 13.1 PL package.
SSI occurred in 25% of liver recipients, with average timing of diagnosis on the 14th day after surgery. Mean duration of hospitalization was significantly longer in patients who experienced SSI than in patients without this complication (35.8 ± 8.9 days vs 25.2 ± 6 days, P < .0001). SSI occurred a little more frequently in men and older recipients, as well as in overweight and underweight patients (not significant). An indication for transplantation did not have an impact on SSI occurrence. The complication was more likely in patients with diabetes and renal failure prior to transplantation (P > .05). Duration of the procedure, blood loss and prolonged drainage did not have any impact on SSIs. SSI was significantly more common in recipients with lower total protein value (P < .0002) and anemia (P < .0002) in early postoperative period.
Among the studied population, a high incidence of SSI was noted, and that some of the identified risk factors differ from those described in the literature.
本研究旨在对肝移植患者手术部位感染（SSI）的发生情况进行单中心评估，并试图确定可能导致这一并发症的因素。
对2016年和2017年接受首次肝移植的60例成年患者的病历进行分析。评估了术前、术中和术后的选定因素。使用StatSoft Statistica 13.1 PL软件包进行统计分析。
25%的肝移植受者发生了SSI，平均诊断时间为术后第14天。发生SSI的患者平均住院时间显著长于未发生该并发症的患者（35.8±8.9天对25.2±6天，P<.0001）。男性、年龄较大的受者以及超重和体重过轻的患者中SSI的发生率略高（无统计学意义）。移植指征对SSI的发生没有影响。移植前患有糖尿病和肾衰竭的患者发生该并发症的可能性更高（P>.05）。手术时间、失血量和引流时间延长对SSI均无影响。术后早期总蛋白值较低（P<.0002）和贫血（P<.0002）的受者中SSI明显更常见。
在研究人群中，SSI的发生率较高，且一些已确定的危险因素与文献中描述的不同。
