Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.
Institute of Occupational and Social Medicine and Health Services Research, University of Tübingen, Tübingen, Germany.
Eur Eat Disord Rev. 2020 Sep;28(5):492-512. doi: 10.1002/erv.2741. Epub 2020 May 3.
The recommendation for conventional body weight loss (BWL) treatment in obesity is 5-10%. It is not clear whether BWL is similar across the three different body mass index (BMI) obesity classes. The aim was to provide an overview on BWL across these classes in moderate lifestyle/diet intervention programs.
A systematic literature search was conducted and the evidence of randomized controlled trials (RCTs) and pre-post design studies synthesized. The outcome was BWL.
For RCTs, mean BWL in the intervention group was 3.6 kg (class I) and 5.3 kg (class II), which equates to 4 and 5% BWL, respectively. None of the assessed class III obesity studies met the inclusion criteria. For pre-post design studies, mean BWL was 5.4 kg (class I), 5.5 kg (class II) and 7.9 kg (class III), with high variation within and across studies in the latter. This equates to 6, 5 and, 6% BWL, respectively.
BWL of moderate BWL programs are similar across the different obesity classes. For class I obesity, the results differ between RCT and pre-post design studies by 2% BWL. The high variation of BWL in class III obesity might reflect different states of motivation such as the attitude towards bariatric surgery.
肥胖症常规体重减轻（BWL）治疗的建议为 5-10%。目前尚不清楚 BWL 在三种不同的体重指数（BMI）肥胖类别中是否相似。本研究旨在提供中等生活方式/饮食干预方案中这些类别中 BWL 的概述。
进行了系统的文献检索，并对随机对照试验（RCT）和前后设计研究的证据进行了综合。主要结局为 BWL。
对于 RCT，干预组的平均 BWL 为 3.6 公斤（I 类）和 5.3 公斤（II 类），分别相当于 4%和 5%的 BWL。评估的 III 类肥胖研究均不符合纳入标准。对于前后设计研究，平均 BWL 分别为 5.4 公斤（I 类）、5.5 公斤（II 类）和 7.9 公斤（III 类），后者的研究内和研究间变异较大。分别相当于 6%、5%和 6%的 BWL。
不同肥胖类别的中等 BWL 方案的 BWL 相似。对于 I 类肥胖症，RCT 和前后设计研究之间的 BWL 差异为 2%。III 类肥胖症中 BWL 的高变异性可能反映了不同的动机状态，例如对减肥手术的态度。
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