光笼型 FRET 纳米闪烁体用于细胞内 microRNA 成像。
Photocaged FRET nanoflares for intracellular microRNA imaging.
机构信息
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, China.
出版信息
Chem Commun (Camb). 2020 Jun 7;56(45):6126-6129. doi: 10.1039/d0cc02395g. Epub 2020 May 4.
In 2015, we proposed FRET nanoflares for intracellular molecular (RNA, H, and K) detection. To improve detection accuracy and achieve on-demand sensing, herein, we developed photocaged FRET nanoflares for spatiotemporal microRNA imaging in living cells. In other words, the probes will not work until they are exposed to UV light.
2015 年，我们提出了 FRET 纳米闪烁用于细胞内分子（RNA、H 和 K）检测。为了提高检测精度并实现按需传感，本文开发了光笼 FRET 纳米闪烁用于活细胞中时空 miRNA 成像。换句话说，只有在探针暴露于紫外光下时，探针才会起作用。
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