Kim Do Hyun, Kim Yeonji, Kim Sung Won, Hwang Se Hwan
Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Head Neck. 2020 Sep;42(9):2635-2643. doi: 10.1002/hed.26186. Epub 2020 May 4.
We evaluated the diagnostic accuracy of narrowband imaging (NBI) in terms of detecting laryngeal cancer compared to that of white light endoscopy (WLE). Two reviewers individually searched the six databases for studies published between the first record date and December 31, 2019. We recorded the numbers of true positives, true negatives, false positives, and false negatives. Quality Assessment of Diagnostic Accuracy Studies ver. 2 software was used to assess the studies. The extent of the inter-rater agreement was also measured. The diagnostic odds ratio (OR) associated with NBI was 87.463 (95% confidence interval [CI]: 46.968, 160.873). The area under the summary receiver operating characteristic curve was 0.954. NBI was more diagnostically accurate than WLE, which was associated with a diagnostic OR of 13.750. NBI affords high diagnostic accuracy, thus supporting a role for NBI in the diagnostic work-up of laryngeal cancer.
我们评估了窄带成像（NBI）与白光内镜检查（WLE）相比在检测喉癌方面的诊断准确性。两名评审员分别在六个数据库中检索了自首个记录日期至2019年12月31日期间发表的研究。我们记录了真阳性、真阴性、假阳性和假阴性的数量。使用诊断准确性研究质量评估版本2软件对研究进行评估。还测量了评分者间一致性的程度。与NBI相关的诊断比值比（OR）为87.463（95%置信区间[CI]：46.968，160.873）。汇总受试者工作特征曲线下面积为0.954。NBI的诊断准确性高于WLE，WLE的诊断OR为13.750。NBI具有较高的诊断准确性，因此支持NBI在喉癌诊断检查中的作用。
