Division of General Surgery, Universitat Autònoma de Barcelona - Hospital del Mar, Barcelona, Spain.
Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, 770 Welch Road, Suite 400, Palo Alto, CA, 94304-5715, USA.
Aesthetic Plast Surg. 2020 Oct;44(5):1387-1395. doi: 10.1007/s00266-020-01736-9. Epub 2020 May 4.
Breast implants have been related to breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). While some research has been conducted to study BIA-ALCL incidence, little is known regarding surgeon concern about the disease.
This study aims to determine surgeon concern about BIA-ALCL within the European plastic surgeon community as related to their practice of breast plastic surgery.
A 27-question online survey was sent to 2353 members of the European Plastic Surgery Society and EURAPS. 240 surgeons responded (10.2%) from 18 different societies. Questions were related to demographics, exposure to BIA-ALCL cases, clinical practices, awareness, and concern. Univariate and multivariable analyses were used.
Of surveyed surgeons, 8% had encountered a case of BIA-ALCL, while 73% were concerned about the disease. The rate of concern seemed to be influenced by seven of the variables studied. However, multivariate analysis demonstrated that none of the combined variables analyzed predicted concern or disclosure of the risks of BIA-ALCL to patients. Textured silicone-filled implants were implicated in the disease (56.5% of cases, P = 0.005). Mentor® and Polytech® were the two brands involved in most of the reported cases (20% each).
Consistent with epidemiological reports worldwide, this study confirms that BIA-ALCL is more prevalent in patients undergoing placement of textured silicone implants, the use of which was greater among surgeons not concerned about the risks of BIA-ALCL. Surgeons appear to approach their patients with similar risk disclosures regardless of practice pattern and type of breast implant used, but not regardless of their concern about the disease.
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乳房植入物与乳腺癌相关间变性大细胞淋巴瘤（BIA-ALCL）有关。虽然已经进行了一些研究来研究 BIA-ALCL 的发病率，但对于外科医生对这种疾病的关注知之甚少。
本研究旨在确定欧洲整形外科学会（EPCS）成员中外科医生对 BIA-ALCL 的关注程度，以及与他们的乳房整形手术实践相关的关注程度。
向欧洲整形外科学会（EPCS）和 EURAPS 的 2353 名成员发送了一份 27 个问题的在线调查。来自 18 个不同协会的 240 名外科医生做出了回应（10.2%）。问题涉及人口统计学、接触 BIA-ALCL 病例、临床实践、意识和关注。使用单变量和多变量分析。
在接受调查的外科医生中，有 8%的人遇到过 BIA-ALCL 病例，而 73%的人对此病表示担忧。关注的比率似乎受到所研究的七个变量的影响。然而，多变量分析表明，在所分析的组合变量中，没有一个可以预测对 BIA-ALCL 的关注或向患者披露其风险。纹理硅胶填充植入物与该疾病有关（56.5%的病例，P=0.005）。Mentor®和 Polytech®是报告的大多数病例中涉及的两个品牌（各占 20%）。
与全球流行病学报告一致，本研究证实 BIA-ALCL 在接受纹理硅胶植入物植入的患者中更为常见，而不关注 BIA-ALCL 风险的外科医生使用这种植入物的比例更高。外科医生似乎对其患者进行了类似的风险披露，无论其实践模式和使用的乳房植入物类型如何，但并不取决于他们对疾病的关注程度。
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