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心脏磁共振成像在主动脉瓣狭窄中的应用。

Usefulness of Cardiac Magnetic Resonance Imaging in Aortic Stenosis.

机构信息

Department of Cardiology (Y.B., C.T.), Amiens University Hospital, France.

UR UPJV 7517, Jules Verne University of Picardie, Amiens, France (Y.B., S.M., C.T.).

出版信息

Circ Cardiovasc Imaging. 2020 May;13(5):e010356. doi: 10.1161/CIRCIMAGING.119.010356. Epub 2020 May 6.

Abstract

The objective of this review is to provide an overview of the role of cardiac magnetic resonance (CMR) in aortic stenosis (AS). Although CMR is undeniably the gold standard for assessing left ventricular volume, mass, and function, the assessment of the left ventricular repercussions of AS by CMR is not routinely performed in clinical practice, and its role in evaluating and quantifying AS is not yet well established. CMR is an imaging modality integrating myocardial function and disease, which could be particularly useful in a pathology like AS that should be considered as a global myocardial disease rather than an isolated valve disease. In this review, we discuss the emerging potential of CMR for the diagnosis and prognosis of AS. We detail its utility for studying all aspects of AS, including valve anatomy, flow quantification, left ventricular volumes, mass, remodeling, and function, tissue mapping, and 4-dimensional flow magnetic resonance imaging. We also discuss different clinical situations where CMR could be useful in AS, for example, in low-flow low-gradient AS to confirm the low-flow state and to understand the reason for the left ventricular dysfunction or when there is a suspicion of associated cardiac amyloidosis.

摘要

本文旨在概述心脏磁共振(CMR)在主动脉瓣狭窄(AS)中的作用。尽管 CMR 无疑是评估左心室容积、质量和功能的金标准,但在临床实践中并未常规进行 CMR 评估 AS 对左心室的影响,其在评估和量化 AS 中的作用也尚未得到充分证实。CMR 是一种整合心肌功能和疾病的成像方式,对于 AS 等应被视为全身性心肌疾病而非单纯瓣膜疾病的病理情况,可能特别有用。在本文中,我们讨论了 CMR 在 AS 的诊断和预后中的新兴潜力。我们详细介绍了 CMR 在研究 AS 各个方面的应用,包括瓣膜解剖结构、流量量化、左心室容积、质量、重构和功能、组织绘图和 4 维血流磁共振成像。我们还讨论了 CMR 在 AS 中的不同临床情况中的应用,例如在低流量低梯度 AS 中,用于确认低流量状态并了解左心室功能障碍的原因,或者怀疑存在相关的心脏淀粉样变性时。

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