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Phylotastic:通过灵活、即时提供系统发育树来改善对生命之树知识的获取。

Phylotastic: Improving Access to Tree-of-Life Knowledge With Flexible, on-the-Fly Delivery of Trees.

作者信息

Nguyen Van D, Nguyen Thanh H, Tayeen Abu Saleh Md, Laughinghouse H Dail, Sánchez-Reyes Luna L, Wiggins Jodie, Pontelli Enrico, Mozzherin Dmitry, O'Meara Brian, Stoltzfus Arlin

机构信息

Department of Computer Science, New Mexico State University, Las Cruces, NM, USA.

Institute for Bioscience and Biotechnology Research, Rockville, MD, USA.

出版信息

Evol Bioinform Online. 2020 Apr 6;16:1176934319899384. doi: 10.1177/1176934319899384. eCollection 2020.

Abstract

A comprehensive phylogeny of species, i.e., a tree of life, has potential uses in a variety of contexts, including research, education, and public policy. Yet, accessing the tree of life typically requires special knowledge, complex software, or long periods of training. The Phylotastic project aims make it as easy to get a phylogeny of species as it is to get driving directions from mapping software. In prior work, we presented a design for an open system to validate and manage taxon names, find phylogeny resources, extract subtrees matching a user's taxon list, scale trees to time, and integrate related resources such as species images. Here, we report the implementation of a set of tools that together represent a robust, accessible system for on-the-fly delivery of phylogenetic knowledge. This set of tools includes a web portal to execute several customizable workflows to obtain species phylogenies (scaled by geologic time and decorated with thumbnail images); more than 30 underlying web services (accessible via a common registry); and code toolkits in R and Python (allowing others to develop custom applications using Phylotastic services). The Phylotastic system, accessible via http://www.phylotastic.org, provides a unique resource to access the current state of phylogenetic knowledge, useful for a variety of cases in which a tree extracted quickly from online resources (as distinct from a tree custom-made from character data) is sufficient, as it is for many casual uses of trees identified here.

摘要

物种的综合系统发育,即生命之树,在包括研究、教育和公共政策等各种背景下都有潜在用途。然而,获取生命之树通常需要专业知识、复杂软件或长时间培训。Phylotastic项目旨在使获取物种系统发育图谱像从地图软件获取驾车路线一样容易。在之前的工作中,我们提出了一个开放系统的设计,用于验证和管理分类单元名称、查找系统发育资源、提取与用户分类单元列表匹配的子树、将树按时间尺度缩放以及整合相关资源,如物种图像。在这里,我们报告了一组工具的实现,这些工具共同构成了一个强大且易于使用的系统,用于即时提供系统发育知识。这组工具包括一个门户网站,用于执行几个可定制的工作流程以获取物种系统发育图谱(按地质时间缩放并配有缩略图);30多个底层网络服务(可通过一个公共注册中心访问);以及R和Python代码工具包(允许其他人使用Phylotastic服务开发定制应用程序)。可通过http://www.phylotastic.org访问的Phylotastic系统提供了一个独特的资源,可用于获取系统发育知识的当前状态,适用于各种情况,即从在线资源快速提取的树(与根据特征数据定制的树不同)就足够了,就像这里确定的许多对树的随意使用情况一样。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5612/7192527/379031d720d4/10.1177_1176934319899384-fig1.jpg

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