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脉冲射频治疗上肢带状疱疹后神经痛对颈神经根的疗效

Efficacy of Pulsed Radiofrequency to Cervical Nerve Root for Postherpetic Neuralgia in Upper Extremity.

作者信息

Ding Yuanyuan, Li Hongxi, Hong Tao, Yao Peng

机构信息

Department of Pain Management, Shengjing Hospital of China Medical University, Shenyang, China.

出版信息

Front Neurosci. 2020 Apr 21;14:377. doi: 10.3389/fnins.2020.00377. eCollection 2020.

DOI:10.3389/fnins.2020.00377
PMID:32372914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7186594/
Abstract

BACKGROUND

Postherpetic neuralgia (PHN) seriously affects a patient's quality of life, and it is urgent to find a method that can effectively alleviate the PHN of the upper extremity.

OBJECTIVE

To observe the Efficacy of pulsed radiofrequency (PRF) to cervical nerve root for PHN in upper extremity under CT guidance.

STUDY DESIGN

Retrospective comparative study.

SETTING

Shengjing Hospital of China Medical University.

METHODS

Fifty patients with PHN in upper extremity were enrolled in Pain Management. Patients were randomized into two groups: cervical nerve root block (A group, = 25) and cervical nerve root PRF (B group, = 25). At each observation time, the general characteristics, visual analog scale (VAS), quality of life scores assessment (SF-36), the total efficacy rate, dosage of antiepileptic and narcotic analgesics, and the incidence of complications were followed up.

RESULTS

Compared with the preoperative, the postoperative VAS decreased, the physical component summary (PCS) and the mental component summary (MCS) increased in both groups ( < 0.05). The differences between group B and group A were statistically significant after 1 month, which could be maintained for 1 year ( < 0.05). The total efficacy rate of group A and group B was 52.0% and 80.0% at 1 Year, respectively. The total efficacy rate of group B was higher than that of group A ( < 0.05). The dosage of antiepileptic and narcotic analgesics in group B decreased significantly, and the decline was significant compared with group A ( < 0.05). The incidence of complications between the two groups were similar ( > 0.05).

CONCLUSION

CT-guided PRF to cervical nerve root for the treatment of PHN in the upper extremity is safe and effective. PRF can replicate the location of pain, precise positioning, reduce trauma, and increased pain relief rate.

摘要

背景

带状疱疹后神经痛(PHN)严重影响患者生活质量,亟待找到一种能有效缓解上肢PHN的方法。

目的

观察CT引导下脉冲射频(PRF)治疗上肢PHN对颈神经根的疗效。

研究设计

回顾性对照研究。

研究地点

中国医科大学附属盛京医院。

方法

选取50例上肢PHN患者纳入疼痛管理。将患者随机分为两组:颈神经根阻滞组(A组,n = 25)和颈神经根PRF组(B组,n = 25)。在各观察时间点,随访患者的一般特征、视觉模拟量表(VAS)评分、生活质量评分(SF - 36)、总有效率、抗癫痫和麻醉性镇痛药用量以及并发症发生率。

结果

与术前相比,两组术后VAS评分均降低,身体成分总结(PCS)和精神成分总结(MCS)均升高(P < 0.05)。B组与A组在术后1个月时差异有统计学意义,且可维持1年(P < 0.05)。1年时A组和B组的总有效率分别为52.0%和80.0%。B组总有效率高于A组(P < 0.05)。B组抗癫痫和麻醉性镇痛药用量显著减少,与A组相比下降明显(P < 0.05)。两组并发症发生率相似(P > 0.05)。

结论

CT引导下颈神经根PRF治疗上肢PHN安全有效。PRF能重现疼痛部位,定位精确,减少创伤,提高疼痛缓解率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/5539fa941ed7/fnins-14-00377-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/9b08bbbb8b81/fnins-14-00377-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/cfe81defd5fa/fnins-14-00377-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/a4588116516e/fnins-14-00377-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/56bfa41290ca/fnins-14-00377-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/5539fa941ed7/fnins-14-00377-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/9b08bbbb8b81/fnins-14-00377-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/cfe81defd5fa/fnins-14-00377-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/a4588116516e/fnins-14-00377-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/56bfa41290ca/fnins-14-00377-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b884/7186594/5539fa941ed7/fnins-14-00377-g005.jpg

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