Rezaee Michael E, Ren Bing, Sverrisson Einar F, Seigne John D, Dagrosa Lawrence M
Section of Urology, Department of Surgery, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, 03756, USA.
Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, 03756, USA.
Urol Case Rep. 2020 Apr 24;32:101222. doi: 10.1016/j.eucr.2020.101222. eCollection 2020 Sep.
Interpretation of multiparametric magnetic resonance imaging (mpMRI) for prostate cancer diagnosis and staging can be challenging and, in some cases, benign prostate disease can mimic locally advanced malignancy. We present the case of a 57 year-old male with biopsy-proven Gleason 3 + 4 prostate cancer and a preoperative mpMRI showing extraprostatic extension who was later found to have infiltrating malakoplakia on final surgical pathology. This case highlights the importance of recognizing that malakoplakia of the prostate can present as a PI-RADS 5 lesion with extracapsular extension on mpMRI. Such cases can result in wide-excision, non-nerve sparing radical prostatectomies that may be unwarranted.
多参数磁共振成像（mpMRI）用于前列腺癌的诊断和分期的解读可能具有挑战性，在某些情况下，良性前列腺疾病可能会模仿局部晚期恶性肿瘤。我们报告一例57岁男性患者，经活检证实为Gleason 3 + 4前列腺癌，术前mpMRI显示前列腺外侵犯，最终手术病理发现为浸润性软斑病。该病例强调了认识到前列腺软斑病在mpMRI上可表现为PI-RADS 5类病变并伴有包膜外侵犯的重要性。此类病例可能导致广泛切除、不保神经的根治性前列腺切除术，而这可能是不必要的。
