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Persistent High Burden of Advanced HIV Disease Among Patients Seeking Care in South Africa's National HIV Program: Data From a Nationwide Laboratory Cohort.南非国家艾滋病毒规划中寻求治疗的患者中持续存在大量晚期艾滋病疾病负担:来自全国性实验室队列的数据。
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N Engl J Med. 2017 Jul 20;377(3):233-245. doi: 10.1056/NEJMoa1615822.
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乌干达实施“治疗即预防”后,CD4 计数检测次数减少。

Reduction in Baseline CD4 Count Testing Following Human Immunodeficiency Virus "Treat All" Adoption in Uganda.

机构信息

Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.

出版信息

Clin Infect Dis. 2020 Dec 3;71(9):2497-2499. doi: 10.1093/cid/ciaa261.

DOI:10.1093/cid/ciaa261
PMID:32373932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7713677/
Abstract

Baseline CD4 testing rates declined from 73% to 21% between 2013 and 2018 with adoption of "Treat All" in Uganda. Advanced human immunodeficiency virus (HIV) disease (CD4 count < 200 cells/µL) remained common (24% of those tested in 2018, 83% of whom had World Health Organization stage I/II disease). Despite frequent presentation with advanced HIV disease, CD4 testing has declined dramatically.

摘要

在乌干达采用“治疗所有”策略后,2013 年至 2018 年期间,基础 CD4 检测率从 73%下降至 21%。晚期人类免疫缺陷病毒(HIV)疾病(CD4 计数 < 200 个/µL)仍然很常见(2018 年接受检测的人群中有 24%,其中 83%患有世界卫生组织 I/II 期疾病)。尽管经常出现晚期 HIV 疾病,但 CD4 检测却大幅下降。