Marom Gil, Einav Shmuel
School of Mechanical Engineering, Tel Aviv University, Tel Aviv Israel.
Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel.
Rambam Maimonides Med J. 2020 Apr 29;11(2):e0014. doi: 10.5041/RMMJ.10400.
Heart valve diseases are common disorders with five million annual diagnoses being made in the United States alone. All heart valve disorders alter cardiac hemodynamic performance; therefore, treatments aim to restore normal flow. This paper reviews the state-of-the-art clinical and engineering advancements in heart valve treatments with a focus on hemodynamics. We review engineering studies and clinical literature on the experience with devices for aortic valve treatment, as well as the latest advancements in mitral valve treatments and the pulmonic and tricuspid valves on the right side of the heart. Upcoming innovations will potentially revolutionize treatment of heart valve disorders. These advancements, and more gradual enhancements in the procedural techniques and imaging modalities, could improve the quality of life of patients suffering from valvular disease who currently cannot be treated.
心脏瓣膜疾病是常见疾病，仅在美国每年就有500万例诊断。所有心脏瓣膜疾病都会改变心脏的血流动力学性能；因此，治疗旨在恢复正常血流。本文综述了心脏瓣膜治疗领域的最新临床和工程进展，重点关注血流动力学。我们回顾了关于主动脉瓣治疗设备经验的工程研究和临床文献，以及二尖瓣治疗以及心脏右侧肺动脉瓣和三尖瓣治疗的最新进展。即将到来的创新可能会彻底改变心脏瓣膜疾病的治疗方式。这些进展，以及手术技术和成像方式的逐步改进，有望改善目前无法治疗的瓣膜病患者的生活质量。
