Institute of Laboratory Medicine, Hospital of the University of Munich (LMU), Marchioninistr. 15, 81377 Munich, Germany.
Clin Chem Lab Med. 2020 May 5;59(2):287-290. doi: 10.1515/cclm-2020-0339.
In view of the role of pharmacotherapy in medicine, on the one hand, and the powerful technical possibilities that are now available on the other hand, therapeutic drug monitoring is a surprisingly neglected area of laboratory medicine. In this viewpoint article, an "omics approach" to pharmacovigilance and drug monitoring is proposed and discussed. A realistic goal for laboratory medicine in the 21st century should indeed be to enable clinicians to check whether the right drug is present in the right patient with an appropriate blood concentration for each compound.
鉴于药物治疗在医学中的作用，一方面，以及目前可用的强大技术可能性，治疗药物监测是实验室医学中一个令人惊讶的被忽视的领域。在这篇观点文章中，提出并讨论了一种药物警戒和药物监测的“组学方法”。对于 21 世纪的实验室医学来说，一个现实的目标确实应该是使临床医生能够检查对于每个化合物，正确的药物是否以适当的血药浓度存在于正确的患者中。
