探索黑素细胞上黑色素浓缩激素受体和黑色素刺激激素受体的进化史：新鳍亚纲（全骨鱼类）和软骨硬鳞鱼类。

Exploring the evolutionary history of melanin-concentrating and melanin-stimulating hormone receptors on melanophores: neopterygian (holostean) and chondrostean fishes.

作者信息

Sherbrooke W C, Hadley M E

机构信息

Department of Ecology and Evolutionary Biology, University of Arizona, Tucson 85721.

出版信息

Pigment Cell Res. 1988;1(5):344-9. doi: 10.1111/j.1600-0749.1988.tb00130.x.

DOI:10.1111/j.1600-0749.1988.tb00130.x

PMID:3237601

Abstract

The occurrence of melanin-concentrating hormone (MCH) receptors on integumental melanophores was found to extend back in the evolutionary line of ray-finned bony fishes (Actinopterygii) to the group ancestral to modern teleosts, the Holostei. The two species of holosteans studied, Amia calva and Lepisosteus platyrhincus, exhibited changes of melanophore index (melanosome aggregation), indicating responses to MCH and to melatonin but no response to norepinephrine (NE). Polyodon spathula, a species of chondrostean (an older group of bony fishes ancestral to holosteans), failed to respond to MCH, to melatonin, or to NE. Nevertheless, Polyodon skin darkened (melanosome dispersion) in response to melanocyte-stimulating hormone (MSH). The preliminary implication of these observations is that the mechanism of physiological color change involving MCH and its melanophore receptors evolved near the end of the Paleozoic or during the early Mesozoic, just before or early in the evolution of neopterygian (holostean and teleostean) fishes.

摘要

人们发现，在有鳍硬骨鱼（辐鳍鱼纲）的进化谱系中，体被黑素细胞上黑色素浓缩激素（MCH）受体的出现可追溯到现代硬骨鱼的祖先类群全骨鱼。所研究的两种全骨鱼，即雀鳝和钝吻雀鳝，表现出黑素细胞指数的变化（黑素体聚集），表明它们对MCH和褪黑素均有反应，但对去甲肾上腺素（NE）无反应。匙吻鲟是一种软骨硬鳞鱼（全骨鱼的一个较古老的硬骨鱼祖先类群），对MCH、褪黑素或NE均无反应。然而，匙吻鲟的皮肤会因促黑素细胞激素（MSH）而变黑（黑素体分散）。这些观察结果初步表明，涉及MCH及其黑素细胞受体的生理颜色变化机制是在古生代末期或中生代早期，即在新鳍亚纲（全骨鱼和硬骨鱼）鱼类进化之前或早期形成的。