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[新生期去势对雄性大鼠隔复合体中脑神经元结合性类固醇能力的影响]

[Effect of neonatal castration on the capacity of the cerebral neurons in the septal complex of male rats to bind sex steroids].

作者信息

Myslitskiĭ V F

出版信息

Probl Endokrinol (Mosk). 1988 Nov-Dec;34(6):56-9.

PMID:3237667
Abstract

The influence of neonatal castration on neuron capacity to bind septal dorsal, lateral and medial nuclei, Brock's diagonal fold nucleus and terminal streak bed nucleus of radiolabeled sex steroids (3H-testosterone and 3H-estradiol) was studied. Neonatal castration performed on the 1st day of male postnatal life raised the capacity of brain septal complex neurons to uptake sex steroids, mainly 3H-testosterone. The strategic position of the septal complex in the brain and the presence of neurons taking up actively sex steroids indicated an important role of this structure of the limbic system of the brain in the formation of neural mechanisms in the regulation of sex functions in male rats.

摘要

研究了新生期去势对神经元结合放射性标记性类固醇(³H-睾酮和³H-雌二醇)的能力的影响,这些性类固醇的结合部位包括隔区背核、外侧核和内侧核、布罗克斜角带核以及终纹床核。在雄性出生后第1天进行新生期去势,可提高脑隔区复合体神经元摄取性类固醇的能力,主要是³H-睾酮。隔区复合体在脑中的重要位置以及存在能积极摄取性类固醇的神经元,表明脑边缘系统的这一结构在雄性大鼠性功能调节神经机制的形成中具有重要作用。

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