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用于多发性硬化症患者剖宫产的舒更葡糖钠

Sugammadex for Cesarean in a Patient with Multiple Sclerosis.

作者信息

Yılmaz Resul, Uzun Sema Tuncer, Reisli Ruhiye

机构信息

Department of Anesthesiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.

出版信息

Sisli Etfal Hastan Tip Bul. 2019 Jul 5;53(2):195-198. doi: 10.14744/SEMB.2017.07108. eCollection 2019.

DOI:10.14744/SEMB.2017.07108
PMID:32377082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7199839/
Abstract

The aim of the present study was to discuss the management of anesthesia in our case with multiple sclerosis (MS) and to present the effects of sugammadex administration. A 36-year-old pregnant patient with MS disease was followed up for 6 years. She was on steroid treatment. The patient had not suffered the entire pregnancy. In addition to performing routine monitoring, "train of four" (TOF) monitorization was used. General anesthesia was given using propofol and rocuronium. At the end of the operation, muscle relaxation was reversed using sugammadex in the patient with a low TOF score. The patient was discharged on postoperative day 3. The most reliable method should be preferred in patients with MS. In patients under general anesthesia, the muscle relaxant effect is prolonged, and sugammadex can be safely used.

摘要

本研究的目的是讨论我们这位多发性硬化症(MS)患者的麻醉管理,并介绍舒更葡糖钠给药的效果。一名患有MS疾病的36岁孕妇接受了6年的随访。她正在接受类固醇治疗。该患者整个孕期都未出现病情发作。除了进行常规监测外,还使用了“四个成串刺激”(TOF)监测。使用丙泊酚和罗库溴铵进行全身麻醉。手术结束时,对TOF评分较低的患者使用舒更葡糖钠逆转肌肉松弛。患者术后第3天出院。对于MS患者,应首选最可靠的方法。在全身麻醉的患者中,肌肉松弛作用会延长,舒更葡糖钠可以安全使用。

相似文献

1
Sugammadex for Cesarean in a Patient with Multiple Sclerosis.用于多发性硬化症患者剖宫产的舒更葡糖钠
Sisli Etfal Hastan Tip Bul. 2019 Jul 5;53(2):195-198. doi: 10.14744/SEMB.2017.07108. eCollection 2019.
2
Low-Dose or High-Dose Rocuronium Reversed with Neostigmine or Sugammadex for Cesarean Delivery Anesthesia: A Randomized Controlled Noninferiority Trial of Time to Tracheal Intubation and Extubation.新斯的明或舒更葡糖用于剖宫产麻醉时低剂量或高剂量罗库溴铵的逆转:气管插管和拔管时间的随机对照非劣效性试验
Anesth Analg. 2016 May;122(5):1536-45. doi: 10.1213/ANE.0000000000001197.
3
Prolonged neuromuscular blockade and insufficient reversal after sugammadex administration in cesarean section under general anesthesia: a case report.全身麻醉下剖宫产术中使用舒更葡糖钠后神经肌肉阻滞延长及逆转不足:一例病例报告
JA Clin Rep. 2019 Apr 11;5(1):28. doi: 10.1186/s40981-019-0248-8.
4
[Insufficient sugammadex effect in an obese pregnant woman undergoing cesarean section under general anesthesia].
Masui. 2014 Feb;63(2):188-90.
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A suspected case of rocuronium-sugammadex complex-induced anaphylactic shock after cesarean section.剖宫产术后罗库溴铵-舒更葡糖复合物诱发过敏性休克疑似病例。
J Anesth. 2017 Feb;31(1):148-151. doi: 10.1007/s00540-016-2280-4. Epub 2016 Nov 16.
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Case report: Neuromuscular block induced by rocuronium following sugammadex administration.病例报告:罗库溴铵诱导的神经肌肉阻滞在向纳曲酮给药后发生。
J Clin Anesth. 2017 Feb;37:166-167. doi: 10.1016/j.jclinane.2016.11.004. Epub 2017 Jan 11.
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Prospective study of residual neuromuscular block and postoperative respiratory complications in patients reversed with neostigmine versus sugammadex.新斯的明与琥珀酰明胶逆转患者肌松残余与术后呼吸并发症的前瞻性研究。
Minerva Anestesiol. 2016 Jul;82(7):735-42. Epub 2015 Oct 16.
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Use of rocuronium and sugammadex under neuromuscular transmission monitoring in a patient with multiple sclerosis.在一名多发性硬化症患者的神经肌肉传递监测下使用罗库溴铵和舒更葡糖钠。
Saudi J Anaesth. 2017 Oct-Dec;11(4):472-475. doi: 10.4103/sja.SJA_625_16.
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[Efficacy of sugammadex in the reversal of neuromuscular blockade induced by rocuronium in long-duration surgery: under inhaled vs. intravenous anesthesia].舒更葡糖钠在长时间手术中逆转罗库溴铵诱导的神经肌肉阻滞的疗效:吸入麻醉与静脉麻醉对比
Rev Esp Anestesiol Reanim. 2009 Jun-Jul;56(6):349-54. doi: 10.1016/s0034-9356(09)70407-4.
10
[Strategy for Determining the Appropriate Dose of Sugammadex with Monitoring Train-of-four (TOF) Responses at the End of Surgery].[术中监测四个成串刺激(TOF)反应来确定舒更葡糖钠合适剂量的策略]
Masui. 2015 Jun;64(6):586-90.

本文引用的文献

1
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Multiple sclerosis in pregnancy.妊娠合并多发性硬化症
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Sugammadex reversal of rocuronium-induced neuromuscular block in Caesarean section patients: a series of seven cases.七例剖宫产患者罗库溴铵诱导的神经肌肉阻滞用苏伽 939 逆转的研究
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Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.罗库溴铵诱导的神经肌肉阻滞用 sugammadex 逆转与依托咪酯麻醉期间新斯的明的比较:一项随机对照试验的结果。
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Pregnancy and multiple sclerosis.妊娠与多发性硬化症
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Multicentre, parallel-group, comparative trial evaluating the efficacy and safety of sugammadex in patients with end-stage renal failure or normal renal function.多中心、平行组、对照试验,评估舒更葡糖钠在终末期肾衰竭患者或肾功能正常患者中的疗效和安全性。
Br J Anaesth. 2008 Oct;101(4):492-7. doi: 10.1093/bja/aen216. Epub 2008 Jul 23.
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Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.与新斯的明用于顺式阿曲库铵诱导的神经肌肉阻滞逆转相比,舒更葡糖用于罗库溴铵诱导的神经肌肉阻滞逆转更快。
Br J Anaesth. 2008 May;100(5):622-30. doi: 10.1093/bja/aen037. Epub 2008 Apr 2.
10
Anaesthetic considerations for patients with a pre-existing neurological deficit: are neuraxial techniques safe?患有既往神经功能缺损患者的麻醉考量:神经轴索技术安全吗?
Acta Anaesthesiol Scand. 2007 Aug;51(7):831-8. doi: 10.1111/j.1399-6576.2007.01325.x. Epub 2007 May 4.