功能近红外光谱信号的分形性:分析与应用
On fractality of functional near-infrared spectroscopy signals: analysis and applications.
作者信息
Zhu Li, Haghani Sasan, Najafizadeh Laleh
机构信息
Rutgers University, Integrated Systems and NeuroImaging Laboratory, Department of Electrical and Computer Engineering, Piscataway, New Jersey, United States.
University of The District of Columbia, Department of Electrical and Computer Engineering, Washington DC, United States.
出版信息
Neurophotonics. 2020 Apr;7(2):025001. doi: 10.1117/1.NPh.7.2.025001. Epub 2020 Apr 29.
The human brain is a highly complex system with nonlinear, dynamic behavior. A majority of brain imaging studies employing functional near-infrared spectroscopy (fNIRS), however, have considered only the spatial domain and have ignored the temporal properties of fNIRS recordings. Methods capable of revealing nonlinearities in fNIRS recordings can provide new insights about how the brain functions. The temporal characteristics of fNIRS signals are explored by comprehensively investigating their fractal properties. Fractality of fNIRS signals is analyzed using scaled windowed variance (SWV), as well as using visibility graph (VG), a method which converts a given time series into a graph. Additionally, the fractality of fNIRS signals obtained under resting-state and task-based conditions is compared, and the application of fractality in differentiating brain states is demonstrated for the first time via various classification approaches. Results from SWV analysis show the existence of high fractality in fNIRS recordings. It is shown that differences in the temporal characteristics of fNIRS signals related to task-based and resting-state conditions can be revealed via the VGs constructed for each case. fNIRS recordings, regardless of the experimental conditions, exhibit high fractality. Furthermore, VG-based metrics can be employed to differentiate rest and task-execution brain states.
人类大脑是一个具有非线性动态行为的高度复杂系统。然而,大多数采用功能近红外光谱(fNIRS)的脑成像研究仅考虑了空间域,而忽略了fNIRS记录的时间特性。能够揭示fNIRS记录中非线性的方法可以为大脑功能提供新的见解。通过全面研究fNIRS信号的分形特性来探索其时间特征。使用缩放窗口方差(SWV)以及可见性图(VG)来分析fNIRS信号的分形性,可见性图是一种将给定时间序列转换为图形的方法。此外,比较了在静息状态和基于任务的条件下获得的fNIRS信号的分形性,并首次通过各种分类方法证明了分形性在区分脑状态中的应用。SWV分析结果表明fNIRS记录中存在高分形性。结果表明,通过为每种情况构建的可见性图可以揭示与基于任务和静息状态条件相关的fNIRS信号时间特征的差异。无论实验条件如何,fNIRS记录都表现出高分形性。此外,基于可见性图的指标可用于区分静息和任务执行脑状态。
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