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如何对青少年特发性脊柱侧凸患者进行随访?基于桡骨远端和尺骨分类的多中心研究的建议。

How do we follow-up patients with adolescent idiopathic scoliosis? Recommendations based on a multicenter study on the distal radius and ulna classification.

机构信息

Department of Orthopaedic Surgery, Nara Medical University, Shijocho 840, Kashihara, Nara, 634-8521, Japan.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Queen Mary Hospital, Professorial Block, 5th Floor, 102 Pokfulam Road, Pokfulam, Hong Kong, SAR, China.

出版信息

Eur Spine J. 2020 Aug;29(8):2064-2074. doi: 10.1007/s00586-020-06441-4. Epub 2020 May 6.

DOI:10.1007/s00586-020-06441-4
PMID:32377896
Abstract

PURPOSE

To determine the capability of the distal radius and ulna (DRU) classification for predicting the scoliosis progression risk within 1 year in patients with adolescent idiopathic scoliosis (AIS) and to develop simple recommendations for follow-up durations.

METHODS

Medical records of patients with AIS at two tertiary scoliosis referral centers were retrospectively reviewed for their DRU classification and major curve Cobb angles. Baseline DRU grades and Cobb angles with subsequent 1-year follow-up curve magnitudes were studied for scoliosis progression, which was defined as exacerbation of the Cobb angle by ≥ 6°. The relationship between DRU classification and scoliosis progression risk within 1 year was investigated. Patients were divided into three groups according to the Cobb angle (10°-19°, 20°-29°, ≥ 30°).

RESULTS

Of the 205 patients with 283 follow-up visits, scoliosis progression occurred in 86 patients (90 follow-up visits). Radius and ulna grades were significantly related to scoliosis progression (p < 0.001). R6, R7, and U5 grades were significantly related to scoliosis progression risk. The curve progression probability increased as the Cobb angle increased. Cobb angles ≥ 30°, with these grades, led to progression in > 80% of patients within 1 year. Curve progression was less likely for grades R9 and U7. Most patients with more mature DRU grades did not experience progression, even with Cobb angles ≥ 30°.

CONCLUSION

With R6, R7, and U5, scoliosis may progress within a short period; therefore, careful follow-up with short intervals within 6 months is necessary. R9 and U7 may allow longer 1-year follow-up intervals due to the lower progression risk.

摘要

目的

确定桡尺骨远端(DRU)分类在预测青少年特发性脊柱侧凸(AIS)患者 1 年内脊柱侧凸进展风险的能力,并为随访持续时间制定简单的建议。

方法

回顾性分析了两家三级脊柱侧弯转诊中心的 AIS 患者的病历,记录了他们的 DRU 分类和主要曲线 Cobb 角。研究了基线 DRU 分级和随后 1 年随访曲线幅度与脊柱侧凸进展的关系,脊柱侧凸进展定义为 Cobb 角恶化≥6°。研究了 DRU 分类与 1 年内脊柱侧凸进展风险的关系。根据 Cobb 角(10°-19°、20°-29°、≥30°)将患者分为三组。

结果

在 205 例患者 283 次随访中,86 例(90 次随访)发生脊柱侧凸进展。桡骨和尺骨分级与脊柱侧凸进展显著相关(p<0.001)。R6、R7 和 U5 级与脊柱侧凸进展风险显著相关。随着 Cobb 角的增加,曲线进展的概率增加。Cobb 角≥30°,这些分级导致超过 80%的患者在 1 年内进展。R9 和 U7 级的曲线进展可能性较小。大多数具有更成熟的 DRU 分级的患者即使 Cobb 角≥30°也不会进展。

结论

对于 R6、R7 和 U5,脊柱侧凸可能在短时间内进展,因此需要在 6 个月内进行密切随访。由于进展风险较低,R9 和 U7 可能允许更长的 1 年随访间隔。

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