Department of Surgery (Division of Urology), Faculty of Medicine, Kuwait University, P.O. Box 24923, 13110, Safat, Kuwait.
Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
J Robot Surg. 2021 Feb;15(1):125-133. doi: 10.1007/s11701-020-01089-0. Epub 2020 May 6.
Little is known about the pathological features of radical prostatectomy among men living in the Middle East. Although prostate cancer became the most common malignancy among males in some countries in the Middle East, the incidence is much lower compared to western populations. The aim of this study is to analyze pathological features and biochemical recurrence in men who underwent robotic-assisted radical prostatectomy (RARP) in Kuwait. The data on all RARP cases performed by a uro-oncologist (SA) were recorded. A comprehensive database was collected, including demographic, clinical, and pathological data. Between February 2014 and November 2019, 65 RARP cases were performed out of a total of 200 robotic urological procedures. The median follow-up was 41.5 months [inter quartile range (IQR) 27.6-52.7]. Eleven (17%) complications occurred in 7 patients, 64% were early (< 30 days post-operatively) and minor (Clavien I-II). Thirty-five (54%) patients had ≥ pT3 disease. Overall, 12 (18%) patients had a positive surgical margin (PSM), and all had ≥ pT3 disease. Potency and continence rates at 12 months were 82% and 97%, respectively. The mean and SD of the hospital stay were 2.7 ± 1.1 days. Biochemical recurrence (BCR) rate was 10%. Men with prostatic adenocarcinoma treated with RARP in Kuwait show a high incidence of pT3 disease. PSM and BCR rates were similar to multiple reports in the literature. To our knowledge, this is the first report of RARP pathological outcomes in the gulf cooperation council (GCC) region of the Middle East.
中东地区男性行根治性前列腺切除术的病理特征鲜为人知。尽管前列腺癌已成为一些中东国家男性中最常见的恶性肿瘤，但与西方人群相比，其发病率要低得多。本研究旨在分析在科威特行机器人辅助根治性前列腺切除术（RARP）的男性的病理特征和生化复发情况。记录了一位泌尿科肿瘤学家（SA）所行的所有 RARP 病例的数据。收集了一个综合数据库，包括人口统计学、临床和病理数据。2014 年 2 月至 2019 年 11 月，在总共 200 例机器人泌尿外科手术中，有 65 例 RARP 手术。中位随访时间为 41.5 个月[四分位距（IQR）27.6-52.7]。7 名患者中有 11 名（17%）发生了 11 种（17%）并发症，64%为早期（术后<30 天）和轻微（Clavien I-II）并发症。35 名（54%）患者患有≥pT3 疾病。总体而言，12 名（18%）患者有阳性切缘（PSM），且所有患者均患有≥pT3 疾病。12 个月时的勃起功能和控尿率分别为 82%和 97%。平均和标准差的住院时间分别为 2.7±1.1 天。生化复发（BCR）率为 10%。在科威特，接受 RARP 治疗的前列腺腺癌患者中，pT3 疾病发病率较高。PSM 和 BCR 率与文献中的多项报告相似。据我们所知，这是中东海湾合作委员会（GCC）地区首次报道 RARP 病理结果。
