Nars P W, von Tönges V, Rohner F
Padiatr Padol. 1977;12(2):118-26.
59 patients with IRDS treated with CPPV in 1973-1974 are compared with 59 patients treated with IPPV in 1971-1972. With CPPV there was a reduction in mortality from 40.7% to 32.2%. CPPV as compared to IPPV reduced right to left shunting from the 6th hour of life onwards. Elevated oxygen supply was needed for shorter time and time of mechanical ventilation as well as duration of intubation could be reduced. The frequency of pneumothorax during ventilation was unchanged. The frequency of bronchopulmonary dysplasia could be reduced. One third of the surviving patients had neurological symptoms at the age of one year, the frequency was lower in the CPPV group. One patient in the IPPV group was severely damaged. The results obtained are in favour of CPPV as compared to IPPV for mechanical ventilation in patients with IRDS.
将1973 - 1974年接受持续气道正压通气(CPPV)治疗的59例婴儿呼吸窘迫综合征(IRDS)患者与1971 - 1972年接受间歇正压通气(IPPV)治疗的59例患者进行比较。采用CPPV后,死亡率从40.7%降至32.2%。与IPPV相比,CPPV从出生后第6小时起就减少了右向左分流。所需高氧供应时间更短,机械通气时间以及插管持续时间均可缩短。通气期间气胸的发生率未变。支气管肺发育不良的发生率可降低。三分之一的存活患者在1岁时出现神经症状,CPPV组的发生率较低。IPPV组有1例患者严重受损。与IPPV相比,所得结果支持在IRDS患者机械通气中使用CPPV。