食用青黛（Polygonum tinctorium Lour）可改善高脂饮食喂养的 Wistar 大鼠的血清脂质谱。
Treatment with indigo plant (Polygonum tinctorium Lour) improves serum lipid profiles in Wistar rats fed a high-fat diet.
机构信息
Department of Public Health and Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8503, Japan.
Faculity of Human Life Science, Shikoku University, Oujin-cho 123-1, Tokushima 771-1192, Japan.
出版信息
J Med Invest. 2020;67(1.2):158-162. doi: 10.2152/jmi.67.158.
We investigated the effects of Polygonum tinctorium Lour (PTL), a plant commonly known as indigo, on biological parameters in an animal model of high-fat diet-induced obesity. Wistar rats fed a high-fat diet and treated with PTL showed lower serum levels of triglycerides and total cholesterol levels and a higher serum levels of HDL cholesterol than those in Wistar rats fed a high-fat diet without PTL treatment. The weight of mesenteric fat in PTL-treated rats was decreased compared to that in control rats not treated with PTL. In addition, energy metabolic rate in the dark period, but not in the light period, in PTL-treated rats was higher than that in control rats. Although a significant difference was not observed, body weight in PTL-treated rats tended to be decreased compared to that in control rats. The results show that PTL improves serum lipid profiles in Wistar rats with high-fat diet-induced obesity. J. Med. Invest. 67 : 158-162, February, 2020.
我们研究了蓼蓝（Polygonum tinctorium Lour），一种俗称靛青的植物，对高脂肪饮食诱导肥胖动物模型中生物学参数的影响。与未用蓼蓝治疗的高脂肪饮食喂养的 Wistar 大鼠相比，用蓼蓝治疗的大鼠血清甘油三酯和总胆固醇水平降低，高密度脂蛋白胆固醇水平升高。与未用蓼蓝治疗的对照组大鼠相比，蓼蓝治疗组大鼠肠系膜脂肪重量减轻。此外，蓼蓝治疗组大鼠在黑暗期的能量代谢率高于对照组大鼠，但在光照期则没有差异。尽管没有观察到显著差异，但蓼蓝治疗组大鼠的体重有降低的趋势。结果表明，蓼蓝改善了高脂肪饮食诱导肥胖的 Wistar 大鼠的血清脂质谱。医学研究杂志 67：158-162，2020 年 2 月。
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