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妊娠期接种流感疫苗或脑膜炎球菌疫苗与母婴死亡率：随机对照试验的汇总分析。

Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials.

机构信息

From the Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA.

Yale Institute for Global Health.

出版信息

Pediatr Infect Dis J. 2020 Jul;39(7):641-644. doi: 10.1097/INF.0000000000002629.

DOI:10.1097/INF.0000000000002629
PMID:32379201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7279057/
Abstract

This analysis includes pooled data from 2 placebo-controlled maternal influenza immunization trials, with a separate analysis on a meningococcal conjugate vaccine-controlled maternal influenza immunization trial. Maternal influenza immunization was not associated with infant or maternal all-cause mortality in placebo-controlled trials. In the meningococcal conjugate vaccine-controlled trial, there were fewer deaths during low or any influenza circulation weeks among infants whose mothers received meningococcal conjugate vaccine. ClinicalTrials.gov identifiers: NCT01430689, NCT01034254 and NCT02465190.

摘要

本分析包括 2 项安慰剂对照的母亲流感免疫接种试验的汇总数据，以及一项脑膜炎球菌结合疫苗对照的母亲流感免疫接种试验的单独分析。安慰剂对照试验中，母亲流感免疫接种与婴儿或母亲全因死亡率无关。在脑膜炎球菌结合疫苗对照试验中，母亲接种脑膜炎球菌结合疫苗的婴儿在流感低流行或任何流行周的死亡人数更少。ClinicalTrials.gov 标识符：NCT01430689、NCT01034254 和 NCT02465190。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f1c/7279057/4f17b0b7eee5/inf-39-0641-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f1c/7279057/4f17b0b7eee5/inf-39-0641-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f1c/7279057/4f17b0b7eee5/inf-39-0641-g003.jpg

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Infant Hospitalizations and Mortality After Maternal Vaccination.婴儿住院和产妇接种疫苗后的死亡率。
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