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帕金森病伴发抑郁和焦虑的认知行为疗法:系统评价和荟萃分析。

Cognitive behavioral therapy for depression and anxiety of Parkinson's disease: A systematic review and meta-analysis.

机构信息

Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

出版信息

Complement Ther Clin Pract. 2020 May;39:101111. doi: 10.1016/j.ctcp.2020.101111. Epub 2020 Jan 30.

DOI:10.1016/j.ctcp.2020.101111
PMID:32379650
Abstract

OBJECT

To systematically evaluate the effects of cognitive behavioral therapy on anxiety and depression symptoms of patients with Parkinson's disease.

METHODS

Four electronic databases (MEDLINE, EMBASE, CINAHL and the Cochrane Library) to May 2019 were searched. The outcome measure of interest was anxiety and depression. Randomized controlled trials or quasi-experimental studies were included in our review. The included individual study's risk of bias were assessed with the Cochrane Collaboration's tool. And the meta-analyses were performed.

RESULTS

A total of 7 studies were included in the meta-analysis with 191 patients. Meta-analysis indicated observed beneficial effects of cognitive behavioral therapy in the reduction of anxiety and depression for individuals with Parkinson's disease.

CONCLUSIONS

This meta-analysis revealed that cognitive behavioral therapy is effective in relieving depression and anxiety of patients with Parkinson's disease. Medical workers could apply cognitive behavioral therapy into daily routine cares for patients with Parkinson's disease. More studies with high quality and follow-up assessment on this topic are still required.

摘要

目的

系统评价认知行为疗法对帕金森病患者焦虑和抑郁症状的影响。

方法

检索 2019 年 5 月前的 4 个电子数据库(MEDLINE、EMBASE、CINAHL 和 Cochrane Library)。主要结局指标为焦虑和抑郁。纳入的研究为随机对照试验或准实验研究。采用 Cochrane 协作网工具评价纳入研究的偏倚风险,并进行荟萃分析。

结果

共纳入 7 项研究,共计 191 例患者。荟萃分析结果表明,认知行为疗法可降低帕金森病患者的焦虑和抑郁。

结论

本荟萃分析表明,认知行为疗法可有效缓解帕金森病患者的抑郁和焦虑。医务人员可将认知行为疗法应用于帕金森病患者的日常护理中。但仍需要更多高质量、随访评估的相关研究。

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