Ponce-Macotela Martha, Martínez-Gordillo Mario Noé
Laboratorio de Parasitología Experimental del Instituto Nacional de Pediatría, Mexico City, Mexico.
Laboratorio de Parasitología Experimental del Instituto Nacional de Pediatría, Mexico City, Mexico.
Adv Parasitol. 2020;109:341-355. doi: 10.1016/bs.apar.2020.01.012. Epub 2020 Feb 5.
In Mexico, toxocariasis, like some other parasitosis in humans, is not a disease of conventional surveillance or immediate notification. Seroprevalence studies are scarce, six dealing with paediatric populations and eight dealing with adults; the reports were only from four states in Mexico. There were 1596 children, and the seroprevalence was 13.8%. In the case of adults, there were 1827 subjects, and seroprevalence was 4.7%. There is a significant positive association between seroprevalence and the paediatric population P<0.0001 (OR, 3.285; 95% CI, 2.541-4.279). It is advisable to perform competitive ELISAs and add another diagnostic test, such as Western blot or the detection of circulating antigens to reduce diagnostic uncertainty. This neglected parasitosis can be confused with retinoblastoma. Therefore, there is a risk of ocular enucleation. It is necessary to sensitise the authorities of the Ministry of Health and decision-makers, to provide economic support for epidemiological surveillance of this zoonotic parasite.
在墨西哥,弓蛔虫病与人类的其他一些寄生虫病一样,并非传统监测或即时通报的疾病。血清阳性率研究稀缺,其中六项针对儿童群体,八项针对成人;报告仅来自墨西哥的四个州。儿童有1596名,血清阳性率为13.8%。成人有1827名,血清阳性率为4.7%。血清阳性率与儿童群体之间存在显著正相关,P<0.0001(比值比,3.285;95%置信区间,2.541 - 4.279)。建议进行竞争性酶联免疫吸附测定(ELISA)并增加另一种诊断测试,如免疫印迹法或循环抗原检测,以减少诊断不确定性。这种被忽视的寄生虫病可能会与视网膜母细胞瘤混淆。因此,存在眼球摘除的风险。有必要提高卫生部当局和决策者的认识,为这种人畜共患寄生虫的流行病学监测提供经济支持。