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来自繁忙核心脏病学实验室的病例：转甲状腺素蛋白心脏淀粉样变心脏闪烁显像解读中的潜在陷阱

Cases from a busy nuclear cardiology laboratory: Potential pitfalls in the interpretation of cardiac scintigraphy for ATTR cardiac amyloidosis.

作者信息

Wehbe Ramsey M, Kansal Preeti, Holly Thomas A

机构信息

Division of Cardiology, Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

J Nucl Cardiol. 2021 Apr;28(2):653-660. doi: 10.1007/s12350-020-02094-4. Epub 2020 May 7.

DOI:10.1007/s12350-020-02094-4
PMID:32383085
Abstract

Cardiac scintigraphy has emerged as a key diagnostic test for transthyretin cardiac amyloidosis (ATTR-CA). However, there are potential limitations and pitfalls in the interpretation of cardiac scintigraphy for ATTR-CA that are worth noting. We present here a series of three cases which illustrate some of these important principles.

摘要

心脏闪烁扫描已成为转甲状腺素蛋白心脏淀粉样变（ATTR-CA）的关键诊断测试。然而，在解读ATTR-CA的心脏闪烁扫描结果时存在一些潜在的局限性和陷阱，值得注意。我们在此展示三个病例系列，以说明其中一些重要原则。

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本文引用的文献

1
Reproducibility and Repeatability of Assessment of Myocardial Light Chain Amyloidosis Burden Using F-Florbetapir PET/CT.使用 F-氟脱氧葡萄糖 PET/CT 评估心肌轻链淀粉样变性负担的可重复性和可重复性。
J Nucl Cardiol. 2021 Oct;28(5):2004-2010. doi: 10.1007/s12350-019-01961-z. Epub 2019 Nov 22.
2
Screening for Transthyretin Amyloid Cardiomyopathy in Everyday Practice.在日常实践中筛查转甲状腺素蛋白淀粉样心肌病。
JACC Heart Fail. 2019 Aug;7(8):709-716. doi: 10.1016/j.jchf.2019.04.010. Epub 2019 Jul 10.
3
Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.
锝焦磷酸盐闪烁扫描术：转甲状腺素淀粉样变心肌病早期诊断的实用指南。
ESC Heart Fail. 2022 Feb;9(1):251-262. doi: 10.1002/ehf2.13693. Epub 2021 Nov 29.
4
A cardiology fellow's take-home points from ASNC's Webinar: Cases in Tc 99m-PYP evaluation of ATTR cardiac amyloidosis - interpretation and reporting.一位心脏病学研究员从美国核医学与分子影像学会网络研讨会中获得的要点：99m锝焦磷酸钠（Tc 99m-PYP）评估转甲状腺素蛋白淀粉样变心肌病（ATTR心脏淀粉样变性）的病例——解读与报告
J Nucl Cardiol. 2021 Apr;28(2):604-609. doi: 10.1007/s12350-020-02516-3. Epub 2021 Mar 2.
5
Incidental detection of ATTR cardiac amyloidosis.转甲状腺素蛋白型心脏淀粉样变的偶然发现。
J Nucl Cardiol. 2022 Jun;29(3):1030-1033. doi: 10.1007/s12350-020-02467-9. Epub 2021 Jan 10.
6
Comparison of planar with tomographic pyrophosphate scintigraphy for transthyretin cardiac amyloidosis: Perils and pitfalls.平面与断层焦磷酸盐闪烁显像术在转甲状腺素蛋白心脏淀粉样变性中的比较：风险与陷阱。
J Nucl Cardiol. 2021 Feb;28(1):104-111. doi: 10.1007/s12350-020-02328-5. Epub 2020 Sep 8.
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N Engl J Med. 2018 Sep 13;379(11):1007-1016. doi: 10.1056/NEJMoa1805689. Epub 2018 Aug 27.
4
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J Nucl Cardiol. 2020 Feb;27(1):123-132. doi: 10.1007/s12350-018-1365-x. Epub 2018 Jul 18.
5
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JAMA Cardiol. 2016 Nov 1;1(8):880-889. doi: 10.1001/jamacardio.2016.2839.
6
Prognostic Significance of Occult Transthyretin Cardiac Amyloidosis in Patients With Severe Aortic Stenosis Undergoing Surgical Aortic Valve Replacement: An Unrecognized Disease Modifier.隐匿性转甲状腺素蛋白心脏淀粉样变在接受外科主动脉瓣置换术的严重主动脉瓣狭窄患者中的预后意义：一种未被认识的疾病修饰因素。
Circ Cardiovasc Imaging. 2016 Aug;9(8). doi: 10.1161/CIRCIMAGING.116.005320.
7
Pilot study for left ventricular imaging phenotype of patients over 65 years old with heart failure and preserved ejection fraction: the high prevalence of amyloid cardiomyopathy.65岁以上射血分数保留的心力衰竭患者左心室成像表型的初步研究：淀粉样心肌病的高患病率
Int J Cardiovasc Imaging. 2016 Sep;32(9):1403-1413. doi: 10.1007/s10554-016-0915-z. Epub 2016 May 30.
8
Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.非活检诊断心脏转甲状腺素淀粉样变性。
Circulation. 2016 Jun 14;133(24):2404-12. doi: 10.1161/CIRCULATIONAHA.116.021612. Epub 2016 Apr 22.
9
Coexistence of Degenerative Aortic Stenosis and Wild-Type Transthyretin-Related Cardiac Amyloidosis.退行性主动脉瓣狭窄与野生型转甲状腺素蛋白相关心脏淀粉样变性并存。
JACC Cardiovasc Imaging. 2016 Mar;9(3):325-7. doi: 10.1016/j.jcmg.2015.04.012. Epub 2015 Jul 15.
10
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