• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

When Should Clinicians Act on Non-Statistically Significant Results From Clinical Trials?

作者信息

Young Paul J, Nickson Christopher P, Perner Anders

机构信息

Medical Research Institute of New Zealand, Wellington, New Zealand.

Wellington Hospital Intensive Care Unit, Wellington Hospital, Wellington, New Zealand.

出版信息

JAMA. 2020 Jun 9;323(22):2256-2257. doi: 10.1001/jama.2020.3508.

DOI:10.1001/jama.2020.3508
PMID:32383733
Abstract
摘要

相似文献

1
When Should Clinicians Act on Non-Statistically Significant Results From Clinical Trials?临床医生应在何时对临床试验中无统计学显著意义的结果采取行动？
JAMA. 2020 Jun 9;323(22):2256-2257. doi: 10.1001/jama.2020.3508.
2
Is the literature inconclusive about the harm from HES? No.关于羟乙基淀粉的危害，文献尚无定论吗？并非如此。
Intensive Care Med. 2017 Oct;43(10):1523-1525. doi: 10.1007/s00134-016-4275-x. Epub 2016 Mar 23.
3
Is the literature inconclusive about the harm of HES? We are not sure.关于羟乙基淀粉的危害，文献是否尚无定论？我们不确定。
Intensive Care Med. 2017 Oct;43(10):1526-1528. doi: 10.1007/s00134-016-4329-0. Epub 2016 Mar 23.
4
Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma).一项随机对照研究：FIRST 试验（严重创伤复苏中的液体）表明羟乙基淀粉复苏可改善穿透性创伤患者的肾功能和乳酸清除率。
Br J Anaesth. 2011 Nov;107(5):693-702. doi: 10.1093/bja/aer229. Epub 2011 Aug 19.
5
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function.羟乙基淀粉（HES）与其他液体疗法：对肾功能的影响。
Cochrane Database Syst Rev. 2013 Jul 23;2013(7):CD007594. doi: 10.1002/14651858.CD007594.pub3.
6
Data too important to share: do those who control the data control the message?数据太过重要而不宜分享：掌控数据的人是否也掌控了信息？
BMJ. 2016 Mar 2;352:i1027. doi: 10.1136/bmj.i1027.
7
Hydroxyethyl starch for resuscitation.羟乙基淀粉复苏。
Curr Opin Crit Care. 2013 Aug;19(4):321-5. doi: 10.1097/MCC.0b013e3283632de6.
8
Fluid resuscitation with 6% hydroxyethyl starch (130/0.4) in acutely ill patients: an updated systematic review and meta-analysis.急性病患者中用 6%羟乙基淀粉（130/0.4）进行液体复苏：一项更新的系统评价和荟萃分析。
Anesth Analg. 2012 Jan;114(1):159-69. doi: 10.1213/ANE.0b013e318236b4d6.
9
Is fluid resuscitation with high-volume hydroxyethyl starch safe for the kidney in trauma patients?大剂量羟乙基淀粉进行液体复苏对创伤患者的肾脏是否安全？
Injury. 2015 Aug;46(8):1698-9. doi: 10.1016/j.injury.2015.03.011. Epub 2015 Mar 16.
10
Comments on: Association between hydroxyethyl starch 130/0.4 administration during noncardiac surgery and postoperative acute kidney injury: A propensity score-matched analysis of a large cohort in China.关于《非心脏手术期间给予羟乙基淀粉130/0.4与术后急性肾损伤之间的关联：一项中国大型队列的倾向评分匹配分析》的评论
J Clin Anesth. 2024 Sep;96:111500. doi: 10.1016/j.jclinane.2024.111500. Epub 2024 May 18.

引用本文的文献

1
Clinically meaningful benefit and real-world evidence in Alzheimer's disease research and care.阿尔茨海默病研究与照护中的临床意义上的益处及真实世界证据。
Alzheimers Dement (N Y). 2025 Apr 24;11(2):e70090. doi: 10.1002/trc2.70090. eCollection 2025 Apr-Jun.
2
Interpretation of statistical findings in randomised trials: a survey of statisticians using thematic analysis of open-ended questions.随机试验中统计结果的解读：对使用开放式问题的主题分析的统计学家的调查。
BMC Med Res Methodol. 2024 Oct 29;24(1):256. doi: 10.1186/s12874-024-02366-4.
3
Between Rational Beliefs and the Bedside: Breaking the Boundaries and Bridging the Breach.
在理性信念与床边之间：打破界限，弥合差距。
Dig Dis Sci. 2024 Oct;69(10):3601-3605. doi: 10.1007/s10620-024-08636-x. Epub 2024 Sep 20.
4
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with nonhypoxic ischaemic acute brain injuries and conditions in the intensive care unit (Mega-ROX Brains).在重症监护病房中，比较非低氧缺血性急性脑损伤成人保守与宽松氧合目标的大型随机注册试验的方案和统计分析计划（大型ROX大脑试验）
Crit Care Resusc. 2023 May 20;25(1):53-59. doi: 10.1016/j.ccrj.2023.04.011. eCollection 2023 Mar.
5
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with sepsis in the intensive care unit (Mega-ROX Sepsis).重症监护病房成人脓毒症患者保守与宽松氧合目标比较的大型随机注册试验方案及统计分析计划（Mega-ROX脓毒症研究）
Crit Care Resusc. 2023 May 22;25(2):106-112. doi: 10.1016/j.ccrj.2023.04.008. eCollection 2023 Jun.
6
Clinical Impact of Stump Closure Reinforced With Hemopatch on the Prevention of Clinically Relevant Pancreatic Fistula After Distal Pancreatectomy: A Multicenter Randomized Trial.使用止血贴加强残端闭合对预防胰体尾切除术后临床相关胰瘘的临床影响：一项多中心随机试验
Ann Surg Open. 2021 Feb 10;2(1):e033. doi: 10.1097/AS9.0000000000000033. eCollection 2021 Mar.
7
Cost-effectiveness of Intermittent vs Continuous Pulse Oximetry Monitoring in Infants Hospitalized With Stabilized Bronchiolitis.支气管肺炎住院婴儿间歇性与连续脉搏血氧监测的成本效益比较
JAMA Netw Open. 2022 Nov 1;5(11):e2243609. doi: 10.1001/jamanetworkopen.2022.43609.
8
Role of Dexamethasone and Methylprednisolone Corticosteroids in Coronavirus Disease 2019 Hospitalized Patients: A Review.地塞米松和甲泼尼龙皮质类固醇在2019年冠状病毒病住院患者中的作用：一项综述
Front Microbiol. 2022 Feb 15;13:813358. doi: 10.3389/fmicb.2022.813358. eCollection 2022.
9
Pick your prior: scepticism about sceptical prior beliefs.选择你的先验：对怀疑性先验信念持怀疑态度。
Intensive Care Med. 2022 Mar;48(3):374-375. doi: 10.1007/s00134-021-06602-z. Epub 2021 Dec 17.
10
Randomised clinical trials in critical care: past, present and future.危重病随机临床试验：过去、现在和未来。
Intensive Care Med. 2022 Feb;48(2):164-178. doi: 10.1007/s00134-021-06587-9. Epub 2021 Dec 2.