Warley A
Division of Anatomy, U.M.D.S. St Thomas's Hospital Campus, London, U.K.
Scanning Microsc. 1988 Dec;2(4):2219-26.
The elemental concentrations in thymocytes from control and diabetic rats were studied by use of the techniques of cryofixation and X-ray microanalysis to determine whether any changes occur in the diseased state. Decreases in the concentrations of the elements P and K were found in thymocytes from the subcapsular and cortical regions of the gland in thymus tissue taken 4 days after the onset of diabetes. A decrease in the concentration of Mg was also found in thymocytes from the subcapsular region of the gland. These changes suggest that the metabolism of thymocytes in vivo is altered in the diabetic animals.
通过冷冻固定和X射线微量分析技术研究了对照大鼠和糖尿病大鼠胸腺细胞中的元素浓度，以确定患病状态下是否发生任何变化。在糖尿病发病4天后采集的胸腺组织中，发现腺体被膜下和皮质区域的胸腺细胞中P和K元素浓度降低。在腺体被膜下区域的胸腺细胞中也发现Mg浓度降低。这些变化表明糖尿病动物体内胸腺细胞的代谢发生了改变。
