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1984 - 1986年曼谷人类狂犬病暴露后预防的流行病学情况

Epidemiology of human rabies post-exposure prophylaxis in Bangkok, 1984-1986.

作者信息

Swaddiwudhipong W, Tiyacharoensri C, Singhachai C, Chutivongse S, Sangwanloy O

机构信息

Division of Epidemiology, Ministry of Public Health, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 1988 Dec;19(4):563-9.

PMID:3238466
Abstract

A study was conducted to determine the current situation of human rabies post-exposure prophylaxis (PEP) in Bangkok for the period 1984-1986. A review of all Bangkok residents receiving PEP at the Queen Saovabha Memorial Institute revealed an increasing incidence rate of PEP from 10.1 cases per 10,000 persons in 1984 to 12.6 cases per 10,000 persons in 1986. The highest incidence rate was observed in young males aged 5-14 years. About 68% of individuals receiving PEP had exposures to bites, especially by dogs, and nearly 30% of PEP cases were due to non-bite exposures. Dogs were responsible for 90% of PEP cases, of which 59% were exposed to stray dogs. Exposure to domestic dogs and cats constituted about 36% of PEP. Approximately 55% of persons received PEP for exposures to animal sources not proven rabid. To reduce the number of PEP, the programme should be directed towards the swift reduction of susceptible animals, which can be achieved by effective elimination of stray dogs and immunization of domestic dogs and cats. Massive health education to the public emphasizing the importance of prevention and control of rabies should be undertaken. The programme for control of rabies can be effective if there is an increased awareness and cooperation among professional people, health personnel, and other people in the community.

摘要

一项研究旨在确定1984 - 1986年期间曼谷人类狂犬病暴露后预防(PEP)的现状。对所有在诗丽吉王后纪念研究所接受PEP的曼谷居民进行的回顾显示,PEP的发病率从1984年的每10000人10.1例增加到1986年的每10000人12.6例。最高发病率出现在5 - 14岁的年轻男性中。接受PEP的个体中约68%曾暴露于咬伤,尤其是被狗咬伤,近30%的PEP病例是由于非咬伤暴露。狗导致了90%的PEP病例,其中59%是暴露于流浪狗。暴露于家犬和家猫的情况约占PEP的36%。约55%的人因暴露于未被证实患有狂犬病的动物源而接受PEP。为减少PEP的数量,该计划应致力于迅速减少易感动物,这可通过有效消灭流浪狗以及对家犬和家猫进行免疫来实现。应向公众开展大规模健康教育,强调预防和控制狂犬病的重要性。如果专业人员、卫生人员和社区中的其他人员提高认识并加强合作,狂犬病控制计划就能有效实施。

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