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增强康复路径中管理阿片类药物耐受手术患者的建议。

Recommendations for Managing Opioid-Tolerant Surgical Patients within Enhanced Recovery Pathways.

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

Department of Obstetrics and Gynecology, Naval Medical Center, San Diego, CA, USA.

出版信息

Curr Pain Headache Rep. 2020 May 8;24(6):28. doi: 10.1007/s11916-020-00856-w.

Abstract

PURPOSE OF REVIEW

One of the consequences of the opioid epidemic is an increase in the number of opioid-tolerant patients. These patients are at higher risk for readmission and longer hospital stays following surgery. Enhanced recovery after surgery (ERAS) pathways can be used as a framework for providing high-quality comprehensive care to patient population. It is estimated that as many as 15% of all surgery patients in the USA are receiving opioids going into surgery. The number of patients on medication maintenance therapy with long-acting opioids such as methadone or partial mu receptor agonists like buprenorphine is rising, which poses a challenge for perioperative healthcare providers.

RECENT FINDINGS

Preoperative opioid tolerance is an independent predictor for increased length of hospital stays, high costs, and increased readmission rates following surgery. Given the recent trends, it is likely that more opioid-tolerant patients will require surgery in near future. Enhanced recovery programs can be used to provide a framework for high-quality care to opioid-tolerant patients throughout all phases of the perioperative process. To improve the quality of care of opioid-tolerant patients, we present five general recommendations for clinicians to consider and possibly incorporate into ERAS programs and care protocols. Recommendations include the following: opioid-tolerant patients should not be excluded from ERAS programs; opioid-tolerant patients should be identified preoperatively; programs should establish standard practices for patients on medication maintenance therapy and buprenorphine; opioid-tolerant patients should receive multimodal analgesia perioperatively; and opioid-tolerant patients should receive coordinated follow up after surgery.

摘要

目的综述

阿片类药物流行的后果之一是阿片类药物耐受患者数量的增加。这些患者在手术后再次入院和住院时间延长的风险更高。术后快速康复(ERAS)途径可用作向患者群体提供高质量综合护理的框架。据估计,美国多达 15%的手术患者在手术前接受阿片类药物治疗。接受美沙酮或丁丙诺啡等部分μ 受体激动剂等长效阿片类药物药物维持治疗的患者人数正在增加,这给围手术期医疗保健提供者带来了挑战。

最新发现

术前阿片类药物耐受是手术后住院时间延长、费用增加和再入院率增加的独立预测因素。鉴于最近的趋势,未来可能会有更多的阿片类药物耐受患者需要手术。ERAS 计划可用于为围手术期各个阶段的阿片类药物耐受患者提供高质量护理的框架。为了提高阿片类药物耐受患者的护理质量,我们为临床医生提出了五条一般建议,以供考虑并可能将其纳入 ERAS 计划和护理方案中。建议包括:不应将阿片类药物耐受患者排除在 ERAS 计划之外;应在术前识别阿片类药物耐受患者;计划应制定针对药物维持治疗和丁丙诺啡患者的标准实践;阿片类药物耐受患者应在围手术期接受多模式镇痛;以及阿片类药物耐受患者应在手术后接受协调的随访。

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