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胸主动脉腔内修复术后30天再入院及资源利用的预测因素。

Predictors of 30-day readmission and resource utilization after thoracic endovascular aortic repair.

作者信息

Iyengar Amit, Goel Nicholas J, Kelly John J, Han Jason, Brown Chase R, Khurshan Fabliha, Chen Zehang, Desai Nimesh D

机构信息

Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Eur J Cardiothorac Surg. 2020 Sep 1;58(3):574-582. doi: 10.1093/ejcts/ezaa128.

Abstract

OBJECTIVES

The introduction and expansion of thoracic endovascular aortic repair (TEVAR) have revolutionized the treatment of a variety of thoracic aortic diseases. We sought to evaluate the incidence, causes, predictors and costs associated with 30-day readmission after TEVAR in a nationally representative cohort.

METHODS

Adult patients undergoing isolated TEVAR were identified in the National Readmissions Database from 2010 to 2014. Hospital costs were estimated by converting individual hospital charge data adjusted to 2014 consumer price indices. Multivariable logistic regression was utilized to determine hospital- and patient-level factors associated with readmissions.

RESULTS

A total of 24 983 TEVARs were noted during the study period; the average age of the patients was 65 ± 16 years; 40% were women. The most common indication was an intact thoracic aneurysm (43.5%), followed by aortic dissection (30.5%). The average cost of the index admission was $63 644 ± $52 312; the average hospital stay was 11 ± 14 days; the index mortality rate was 6.7%. Readmissions within 30 days occurred in 17.4% of patients. Indications for readmission were varied; the most common aetiologies were cardiac (17.8%), infectious (16.0%) and pulmonary (12.1%). On multivariable analysis, the strongest predictor of readmission was the diagnosis, with a ruptured thoraco-abdominal aneurysm having the highest readmission burden (adjusted odds ratio 2.23, 1.17-4.24; P = 0.015). Notably, hospital volume did not predict index hospital length of stay, costs or 30-day readmissions (all P > 0.10).

CONCLUSIONS

Annual TEVAR volume was not associated with any of the outcomes assessed. Rather, indication for TEVAR was the strongest predictor for many outcomes. As TEVAR becomes increasingly utilized, a focus on cardiac and vascular diseases may reduce readmissions and improve quality of care.

摘要

目的

胸主动脉腔内修复术(TEVAR)的引入和推广彻底改变了多种胸主动脉疾病的治疗方式。我们试图评估在全国代表性队列中TEVAR术后30天再入院的发生率、原因、预测因素和费用。

方法

在2010年至2014年的国家再入院数据库中识别接受单纯TEVAR的成年患者。通过将根据2014年消费者价格指数调整后的个体医院收费数据进行转换来估算医院费用。采用多变量逻辑回归来确定与再入院相关的医院和患者层面因素。

结果

在研究期间共记录了24983例TEVAR手术;患者的平均年龄为65±16岁;40%为女性。最常见的适应证是完整的胸主动脉瘤(43.5%),其次是主动脉夹层(30.5%)。首次入院的平均费用为63644±52312美元;平均住院时间为11±14天;首次入院死亡率为6.7%。17.4%的患者在30天内再次入院。再入院的适应证各不相同;最常见的病因是心脏方面(17.8%)、感染方面(16.0%)和肺部方面(12.1%)。在多变量分析中,再入院的最强预测因素是诊断,胸腹主动脉瘤破裂的再入院负担最高(调整后的优势比为2.23,1.17 - 4.24;P = 0.015)。值得注意的是,医院规模并不能预测首次住院时间、费用或30天再入院情况(所有P>0.10)。

结论

每年的TEVAR手术量与所评估的任何结果均无关联。相反,TEVAR的适应证是许多结果的最强预测因素。随着TEVAR的使用越来越多,关注心脏和血管疾病可能会减少再入院并提高医疗质量。

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