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先兆流产与妊娠丢失:该问题的当代研究现状

.Threatened miscarriage and pregnancy loss: contemporary aspects of the problem.

作者信息

Nepyivoda Oksana M, Ryvak Tetiana B

机构信息

Department Of Clinical Pharmacy, Pharmacotherapy And Medical Standardization, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.

出版信息

Wiad Lek. 2020;73(5):1021-1027.

PMID:32386388
Abstract

OBJECTIVE

The aim is to examine the state of a miscarriage of pregnancy problem and approaches to its solution based on current Ukrainian and international experience; to investigate a relevant set of terms and their interpretations that are tangible to the above-mentioned problem.

PATIENTS AND METHODS

Materials and methods: modern information sources available for miscarriage and pregnancy loss. System analysis, bibliographic, bibliosemantic, comparative-and-analytical methods were used.

CONCLUSION

Conclusions: A relevant set of terms and their interpretations tangential to the identified problem (n=13) have been researched. It was found that the achievement of rational pharmacotherapy in patients with the threat of miscarriage is complicated mainly by the presence of 4 factors: extragenital pathology, burdened obstetric-gynecological anamnesis, lack of adequate drugs and possibilities of their prescription, especially in the 1st half of pregnancy. Disregarding these factors when prescribing medicines increases the risk of drug-related problems occurrence, prolongation of hospitalization and the adverse outcome of treatment (miscarriage). The results of the analysis of available information flow have shown the existence of terminological ambiguity related to the threat of miscarriage, in particular, there are often the following terms: spontaneous abortion, threatened abortion etc. instead of miscarriage, the threatened miscarriage which are recommended by international experts both in native Ukrainian and foreign researches. Unintended use of inadequate terms, in particular, «pregnancy failure» may form negative influence on women, cause the exaggeration of their condition, induce the feeling of despair, guilt, uncertainty associated with loss of the pregnancy.

摘要

目的

基于当前乌克兰和国际经验,研究妊娠流产问题的现状及其解决方法;调查与上述问题相关的一组术语及其解释。

患者与方法

材料与方法:可获取的关于流产和妊娠丢失的现代信息来源。采用系统分析、文献学、文献语义学、比较分析方法。

结论

结论:研究了与已确定问题相关的一组术语及其解释(n = 13)。发现流产威胁患者实现合理药物治疗主要因4个因素而复杂化:生殖器外疾病、复杂的妇产科病史、缺乏足够的药物及其处方可能性,尤其是在妊娠前半期。开药时忽视这些因素会增加药物相关问题发生、住院时间延长及治疗不良结局(流产)的风险。对现有信息流的分析结果表明,与流产威胁相关存在术语歧义,特别是经常出现以下术语:自然流产、先兆流产等,而非国际专家在乌克兰国内和国外研究中推荐的流产、先兆流产。不恰当术语的不当使用,特别是“妊娠失败”,可能对女性形成负面影响,导致她们夸大自身病情,引发绝望、内疚、与妊娠丢失相关的不确定感。

相似文献

1
.Threatened miscarriage and pregnancy loss: contemporary aspects of the problem.先兆流产与妊娠丢失:该问题的当代研究现状
Wiad Lek. 2020;73(5):1021-1027.
2
Influence of threatened miscarriage on pregnancy and early postpartum period: a case-control report.先兆流产对妊娠及产后早期的影响:一项病例对照研究报告
J Matern Fetal Neonatal Med. 2015 Jul;28(10):1186-9. doi: 10.3109/14767058.2014.947577. Epub 2014 Aug 12.
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Threatened miscarriage as a predictor of obstetric outcome.先兆流产作为产科结局的预测指标。
Obstet Gynecol. 2006 Apr;107(4):845-50. doi: 10.1097/01.AOG.0000206186.91335.9a.
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Do serum leptin levels have a role in the prediction of pregnancy outcome in case of threatened miscarriage?在先兆流产的情况下,血清瘦素水平在预测妊娠结局方面是否起作用?
Clin Endocrinol (Oxf). 2006 Dec;65(6):772-5. doi: 10.1111/j.1365-2265.2006.02665.x.
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The problem of miscarriage in multiple pregnancy.多胎妊娠中的流产问题。
Wiad Lek. 2018;71(7):1195-1199.
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Obstetric outcome after threatened miscarriage with and without a hematoma on ultrasound.超声检查有或无血肿的先兆流产后的产科结局
Obstet Gynecol. 2003 Sep;102(3):483-7. doi: 10.1016/s0029-7844(03)00580-5.
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Acupuncture as a therapeutic treatment option for threatened miscarriage.针灸作为治疗 threatened miscarriage 的一种治疗选择。
BMC Complement Altern Med. 2012 Mar 22;12:20. doi: 10.1186/1472-6882-12-20.
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Stress, anxiety, intolerance of uncertainty, and psychological well-being characteristics of pregnant women with and without threatened miscarriage: a case-control study.有和没有先兆流产的孕妇的压力、焦虑、不确定性容忍度和心理健康特征:一项病例对照研究。
J Obstet Gynaecol. 2022 Nov;42(8):3577-3583. doi: 10.1080/01443615.2022.2158319. Epub 2022 Dec 19.
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Obstetric outcome and cytokine levels in threatened miscarriage.先兆流产的产科结局和细胞因子水平。
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Adverse outcomes of Chinese medicines used for threatened miscarriage: a systematic review and meta-analysis.中药治疗先兆流产不良结局的系统评价和 Meta 分析。
Hum Reprod Update. 2012 Sep-Oct;18(5):504-24. doi: 10.1093/humupd/dms025. Epub 2012 Jun 2.

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