Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Am J Ophthalmol. 2020 Sep;217:182-188. doi: 10.1016/j.ajo.2020.04.039. Epub 2020 May 6.
To compare outcomes between Müller muscle conjunctival resection (MMCR) ptosis repair and external levator resection (ELR) in patients with severe involutional blepharoptosis.
Retrospective, interventional, comparative case series.
A retrospective review was performed of patients who underwent ptosis repair between 2012 and 2019. Inclusion criteria were patients who underwent MMCR or ELR ptosis repair, patients with complete documentation of preoperative eyelid measurements, and patients with documentation of postoperative outcome. The main outcome measure was surgical failure, defined as patient-reported or physician-reported dissatisfaction with postoperative eyelid height or postoperative upper margin reflex distance (MRD1) of less than 2 mm. Severe ptosis was described as an MRD1 of 0 or worse. Outcome analysis was also performed after stratification for concomitant blepharoplasty performed at the time of ptosis repair.
A total of 231 patients (372 eyelids) met the study criteria, of which 142 eyelids had severe ptosis. Comparing outcomes of MMCR vs ELR in patients with severe ptosis, there was a statistically significant higher rate of success after MMCR (P = .0143). The rate of ptosis repair success in eyelids that underwent MMCR was 97.2% and 90.9% in patients with severe ptosis and mild/moderate ptosis, respectively (P = .42). In eyelids that underwent ELR, the rate of ptosis repair success was 77.4% and 85% in eyelids with severe ptosis and mild/moderate ptosis, respectively (P = .15). Concomitant blepharoplasty did not affect ptosis repair outcomes in any group.
MMCR ptosis repair is an effective approach in treating patients with severe ptosis, and it may offer superior outcomes to ELR. In patients with good responses to phenylephrine, MMCR may offer an efficient and highly efficacious surgery regardless of presenting MRD1.
比较 Müller 肌结膜切除术(MMCR)和外直肌切除术(ELR)治疗重度退行性上睑下垂的效果。
回顾性、干预性、对比病例系列研究。
对 2012 年至 2019 年间接受上睑下垂修复手术的患者进行回顾性分析。纳入标准为接受 MMCR 或 ELR 上睑下垂修复术的患者、术前眼睑测量有完整记录的患者、术后结局有记录的患者。主要结局指标为手术失败,定义为患者或医生报告对术后眼睑高度不满意或术后上睑缘反射距离(MRD1)小于 2mm。重度上睑下垂定义为 MRD1 为 0 或更差。对同时行上睑成形术的患者进行分层后,也进行了结果分析。
共有 231 名患者(372 只眼)符合研究标准,其中 142 只眼患有重度上睑下垂。比较 MMCR 与 ELR 治疗重度上睑下垂的效果,MMCR 的成功率明显更高(P=0.0143)。MMCR 治疗重度上睑下垂和轻度/中度上睑下垂的成功率分别为 97.2%和 90.9%(P=0.42)。ELR 治疗重度上睑下垂和轻度/中度上睑下垂的成功率分别为 77.4%和 85%(P=0.15)。在任何一组中,同时行上睑成形术都不会影响上睑下垂修复的效果。
MMCR 上睑下垂修复术是治疗重度上睑下垂的有效方法,其效果可能优于 ELR。对于对苯肾上腺素反应良好的患者,无论术前 MRD1 如何,MMCR 可能提供一种高效且高度有效的手术。