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经结膜折叠手术与去氧肾上腺素试验阳性和阴性的退行性上睑下垂组相比的疗效

Efficacy of Transconjunctival Tucking Surgery in Comparison With the Phenylephrine-test Positive and Negative Involutional Blepharoptosis Groups.

作者信息

Ogasawara Kosuke

机构信息

From the Medical Corporation, Ogasawara Eye Clinic, Morioka, Japan.

出版信息

Plast Reconstr Surg Glob Open. 2025 Jul 16;13(7):e6902. doi: 10.1097/GOX.0000000000006902. eCollection 2025 Jul.

Abstract

BACKGROUND

This study aimed to determine whether there is a significant difference in the efficacy of transconjunctival tucking of the Müller muscle and levator aponeurosis in patients with involutional blepharoptosis who tested positive or negative on the phenylephrine test.

METHODS

The analysis involved 64 eyes of 42 patients with levator muscle function of the upper eyelid of 8 mm or more and a margin reflex distance 1 (MRD-1) of less than 2 mm. Patients who tested positive and negative for 5% phenylephrine were allocated to group A (41 eyes of 26 patients) and group B (23 eyes of 16 patients), respectively. The efficacy of surgery (ΔMRD-1) was compared by subtracting preoperative MRD-1 from postoperative MRD-1. Multiple comparison tests were performed to evaluate changes in MRD-1 and ΔMRD-1 every 3 months from 3 to 12 months after transconjunctival tucking of the Müller muscle and levator aponeurosis.

RESULTS

Regarding the mean ΔMRD-1 values at 3, 6, and 12 months postoperatively, the values at 6 and 12 months were significantly lower in group A than in group B, with 2.31, 1.98, and 1.81 mm, respectively, in group A and 2.73, 2.71, and 2.50 mm, in group B ( = 0.03 at 6 mo and = 0.041 at 12 mo).

CONCLUSIONS

The efficacy of transconjunctival tucking of the Müller muscle and levator aponeurosis was greater in group B than in group A, and the results were more stable. This is an interesting finding when considering the successful mechanism in the present surgical method.

摘要

背景

本研究旨在确定在对去氧肾上腺素试验呈阳性或阴性的退行性上睑下垂患者中,经结膜折叠 Müller 肌和提上睑肌腱膜的疗效是否存在显著差异。

方法

分析纳入了 42 例患者的 64 只眼,这些患者上睑提肌功能为 8 毫米或以上,且边缘反射距离 1(MRD-1)小于 2 毫米。5%去氧肾上腺素试验呈阳性和阴性的患者分别被分配到 A 组(26 例患者的 41 只眼)和 B 组(16 例患者的 23 只眼)。通过用术后 MRD-1 减去术前 MRD-1 来比较手术疗效(ΔMRD-1)。在经结膜折叠 Müller 肌和提上睑肌腱膜术后 3 至 12 个月期间,每 3 个月进行多次比较试验,以评估 MRD-1 和 ΔMRD-1 的变化。

结果

关于术后 3、6 和 12 个月时的平均 ΔMRD-1 值,A 组 6 个月和 12 个月时的值显著低于 B 组,A 组分别为 2.31、1.98 和 1.81 毫米,B 组为 2.73、2.71 和 2.50 毫米(6 个月时 P = 0.03,12 个月时 P = 0.041)。

结论

经结膜折叠 Müller 肌和提上睑肌腱膜的疗效在 B 组中比 A 组更大,且结果更稳定。考虑到当前手术方法的成功机制,这是一个有趣的发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4097/12266903/cb2e0cc45b04/gox-13-e6902-g002.jpg

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