Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02115, USA.
Department of Pathology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Bader 104, Boston, MA 02115, USA.
Surg Pathol Clin. 2020 Jun;13(2):217-233. doi: 10.1016/j.path.2020.02.005.
Pediatric gliomas are biologically distinct from adult gliomas. Although recent literature uncovered new genetic alterations, the prognostic implications of these discoveries are still unclear. This article provides an update on the histologic and molecular features with prognostic and/or therapeutic implications in pediatric gliomas.
小儿神经胶质瘤在生物学上有别于成人神经胶质瘤。尽管最近的文献揭示了新的遗传改变，但这些发现的预后意义仍不清楚。本文提供了有关小儿神经胶质瘤具有预后和/或治疗意义的组织学和分子特征的最新信息。
