Shiotsuki Kazuo, Takizawa Kohei, Ono Hiroyuki
Division of Endoscopy, Shizuoka Cancer Center.
Gan To Kagaku Ryoho. 2020 Apr;47(4):563-568.
Endoscopic submucosal dissection(ESD)has been established as a standard treatment for early gastric cancer with low possibility of lymph node metastasis. Based on the results of the multicenter prospective study(JCOG0607), expanded indication for differentiated-type gastric cancer in Gastric Cancer Treatment Guidelines 2014 changed to absolute indication in Gastric Cancer Treatment Guidelines 2018. The other multicenter prospective study(JCOG1009/1010)will reveal the longterm outcomes of ESD for undifferentiated-type gastric cancer. With the advance of an aging society in Japan, the indication and curability of early gastric cancer for elderly patients should be discussed in the future.
内镜下黏膜剥离术（ESD）已成为早期胃癌伴低淋巴结转移可能性的标准治疗方法。基于多中心前瞻性研究（JCOG0607）的结果，《2014年胃癌治疗指南》中分化型胃癌的扩大适应证在《2018年胃癌治疗指南》中变为绝对适应证。另一项多中心前瞻性研究（JCOG1009/1010）将揭示ESD治疗未分化型胃癌的长期疗效。随着日本社会老龄化的加剧，未来应讨论老年患者早期胃癌的适应证和治愈率。
