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[胰腺癌根治术后一年腹膜转移复发致肠梗阻一例]

[A Case of Intestinal Obstruction Caused by Peritoneal Metastatic Recurrence One Year after Radical Operation for Pancreatic Cancer].

作者信息

Ota Hideo, Yokoyama Shigekazu, Honda Shoko, Ito Kazuma, Miyazaki Hidetaka, Ueda Hiroki, Takiguchi Nobuo, Nakai Shigeto, Matsuno Hiroshi, Takeoka Tomohira, Konishi Ken, Okada Kazuyuki, Fukunaga Mutsumi, Kobayashi Kenji

机构信息

Dept. of Gastrointestinal Surgery, Hyogo Prefectural Nishinomiya Hospital.

出版信息

Gan To Kagaku Ryoho. 2020 Apr;47(4):718-721.

Abstract

In December 20XX-1, abdominal enhanced CT of a 73-year-old female patient showed a 28mm-in-diameter pancreatic tail cancer with splenic venous invasion. She underwent neoadjuvant GEM/TS-1 combination chemotherapy but abandoned this chemotherapy due to melena and exanthema. She underwent a distal pancreatectomy with lymph node dissemination. In these pathological findings, the tumor was diagnosed as a pancreatic tail cancer with splenic venous invasion(T3, N0, M0, Stage ⅡA). She underwent adjuvant GEM chemotherapy, but she abandoned this chemotherapy due to exanthema and was managed with observation. In September 20XX, she had a postoperative bowel obstruction and was treated with natural light. However, she had a postoperative bowel obstruction again in July, 20XX+1. Fluoroscopic images revealed stenosis in the intestine located 170 cm from the nasal cavity. She underwent open surgery to manage the bowel obstruction. There was a peritoneal tumor with adhesion to each intestine serosa in 3 areas located 80 cm, 100 cm, and 150 cm from the Treitz ligament. Therefore, she underwent a small intestine resection and anastomosis 70 cm to 110 cm from the Treitz ligament. Pathological findings showed that there was a 3mm-in-diameter adenocarcinoma in this peritoneal tumor. In these findings, this final diagnosis was an adhesive intestinal obstruction caused by peritoneal metastasis. Curative resection for single peritoneal recurrent metastasis might be useful for prognosis prolongation.

摘要

20XX年12月,一名73岁女性患者的腹部增强CT显示胰尾癌,直径28mm,侵犯脾静脉。她接受了吉西他滨/替吉奥联合新辅助化疗,但因黑便和皮疹放弃了该化疗。她接受了胰体尾切除术及淋巴结清扫。在这些病理检查结果中,肿瘤被诊断为侵犯脾静脉的胰尾癌(T3,N0,M0,ⅡA期)。她接受了辅助吉西他滨化疗,但因皮疹放弃了该化疗,之后接受观察。20XX年9月,她出现术后肠梗阻,接受保守治疗。然而,在20XX + 1年7月她再次出现术后肠梗阻。透视图像显示距鼻腔170 cm处的肠道狭窄。她接受了开放手术治疗肠梗阻。在距屈氏韧带80 cm、100 cm和150 cm的3个区域有腹膜肿瘤,与各肠浆膜粘连。因此,她接受了距屈氏韧带70 cm至110 cm的小肠切除及吻合术。病理检查结果显示该腹膜肿瘤中有一个直径3mm的腺癌。在这些检查结果中,最终诊断为腹膜转移导致的粘连性肠梗阻。对单个腹膜复发转移进行根治性切除可能有助于延长预后。

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