Tripler Army Medical Center, Honolulu, HI, USA.
Int J Surg Pathol. 2020 Sep;28(6):637-642. doi: 10.1177/1066896920916243. Epub 2020 May 10.
Vascular transformation of the lymph node sinuses (VTS) is an uncommon phenomenon that is believed to occur secondary to obstruction of efferent lymphatics, frequently occuring in retroperitoneal lymph nodes draining cancer. The nodular subtype of VTS, in particular, can mimic metastatic cancer, such as metastatic renal cell carcinoma with sarcomatoid differentiation, potentially resulting in inaccurate tumor grading and/or staging. We present a case of nodular VTS mimicking metastatic renal cell carcinoma with sarcomatoid differentiation in a patient with high-grade clear cell renal cell carcinoma, and explore the relevant differential diagnosis. Awareness of VTS is essential to avoid misdiagnosis of this benign and curative condition.
淋巴结窦血管转化（VTS）是一种不常见的现象，据信是继发于输出淋巴管阻塞，常发生于腹膜后引流癌症的淋巴结中。特别是结节型 VTS 可模拟转移性癌症，如伴肉瘤样分化的转移性肾细胞癌，可能导致肿瘤分级和/或分期不准确。我们报告了一例高级别透明细胞肾细胞癌患者中结节型 VTS 模拟伴肉瘤样分化的转移性肾细胞癌的病例，并探讨了相关的鉴别诊断。了解 VTS 对于避免对这种良性和可治愈疾病的误诊至关重要。
